SCHEMBL16660740

SCHEMBL16660740

CCN(C(=O)c1cnn([C@H]2CC[C@@H](C#N)CC2)c1C)c1ccnnc1

nearest known ligand 0.37

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
OXTR P30559 2/20 0.37
CYP3A4 P08684 1/20 0.32
CYP2C9 P11712 1/20 0.32
CYP2B6 P20813 1/20 0.32
CYP2C19 P33261 1/20 0.32
LRRK2 Q5S007 1/20 0.32
PREP P48147 1/20 0.31
PDE7A Q13946 1/20 0.30
SPR P35270 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16660729 0.88 OXTR (0.39) OXTRCYP3A4CYP2C9CYP2B6CYP2C19
SCHEMBL16660742 0.88 OXTR (0.40) OXTRCYP3A4CYP2C9CYP2B6CYP2C19
SCHEMBL16660731 0.87 OXTR (0.40) OXTRCYP3A4CYP2C9CYP2B6CYP2C19
SCHEMBL16660730 0.85 OXTR (0.37) OXTRCYP3A4CYP2C9CYP2B6CYP2C19
SCHEMBL16654466 0.85 OXTR (0.37) OXTRCYP3A4CYP2C9CYP2B6CYP2C19
SCHEMBL16973269 0.83 TRPV4 (0.38) OXTRCYP3A4CYP2C9CYP2B6CYP2C19
SCHEMBL16654825 0.82 OXTR (0.35) OXTRCYP3A4CYP2C9CYP2B6CYP2C19
SCHEMBL16660743 0.80 OXTR (0.39) OXTRCYP3A4CYP2C9CYP2B6CYP2C19
SCHEMBL16660732 0.78 OXTR (0.38) OXTRCYP3A4CYP2C9CYP2B6CYP2C19
SCHEMBL16660741 0.78 OXTR (0.40) OXTRCYP3A4CYP2C9CYP2B6CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015055497-A1 SUBSTITUTED PESTICIDAL PYRAZOLE COMPOUNDS BASF SE (DE) 2015-04-23 WO disclosed