Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | CMA1 | P23946 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 8/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 8/20 | 0.38 |
| ▸ | USP2 | O75604 | 7/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 7/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 6/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TRPC1 | P48995 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18834234 | 0.78 | TRPC5 (0.43) | ALDH1A1KMT2AMEN1SMN1; SMN2CHRM5 | |
| SCHEMBL16122939 | 0.77 | GRIN1 (0.43) | ALDH1A1KMT2AMAPTPOLB | |
| SCHEMBL19375602 | 0.76 | ADORA3 (0.43) | TSHRALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL20432257 | 0.75 | TRPC5 (0.50) | TSHRALDH1A1CHRM5CYP3A4CYP2C19 | |
| SCHEMBL17772730 | 0.75 | ALDH1A1 (0.77) | TSHRALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL16122914 | 0.73 | TSHR (0.41) | TSHRKMT2AMAPTLMNAALOX15 | |
| SCHEMBL16363950 | 0.73 | TRPC5 (0.49) | TSHRALDH1A1KMT2AMEN1CYP3A4 | |
| SCHEMBL16364030 | 0.72 | TRPC5 (0.47) | CHRM5TRPC1TRPC4TRPC5 | |
| SCHEMBL18834618 | 0.71 | TRPC5 (0.54) | CHRM5CYP2C9TRPC1TRPC4TRPC5 | |
| SCHEMBL16364000 | 0.71 | TRPC5 (0.48) | CHRM5CYP2C9TRPC1TRPC4TRPC5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014152287-A9 | SUBSTITUTED XANTHINES AND METHODS OF USE THEREOF | HYDRA BIOSCIENCES, INC. (US) | 2015-04-23 | — | — | WO | disclosed |