SCHEMBL16664827

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL8570718	0.72	KDM4E (0.51)	KDM4EGSK3BCDK5CDK5R1GAA
	SCHEMBL8088621	0.72	USP8 (0.40)	KDM4EALDH1A1HPGDKMT2AMEN1
	SCHEMBL15352389	0.71	SMN1; SMN2 (0.51)	MPOKDM4EALDH1A1HPGDSMN1; SMN2
	SCHEMBL4763653	0.71	KDM4E (0.63)	MPOKDM4EALDH1A1HPGDSMN1; SMN2
	SCHEMBL31747891	0.70	MPO (0.57)	MPOKDM4EALDH1A1HPGDSMN1; SMN2
	SCHEMBL31546460	0.70	FGFR1 (0.47)	MPOALDH1A1SMN1; SMN2RAB9AC1R
	SCHEMBL18228978	0.70	ALDH1A1 (0.50)	MPOKDM4EALDH1A1HPGDSMN1; SMN2
	SCHEMBL29429633	0.70	CA1 (0.71)	KDM4EALDH1A1HPGDSMN1; SMN2RAB9A
	SCHEMBL301996	0.70	CA1 (0.71)	KDM4EALDH1A1HPGDSMN1; SMN2RAB9A
	SCHEMBL29788337	0.70	CA1 (0.71)	KDM4EALDH1A1HPGDSMN1; SMN2RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.