SCHEMBL1666509

SCHEMBL1666509

NC(CCc1ccc(Oc2ccccc2O)cc1)C(=O)O

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC1A5 Q15758 6/20 0.51
LTA4H P09960 3/20 0.46
FFAR1 O14842 2/20 0.45
MMP12 P39900 1/20 0.44
MMP13 P45452 1/20 0.44
TTR P02766 1/20 0.42
KDM4E B2RXH2 1/20 0.42
USP2 O75604 1/20 0.42
EGFR P00533 1/20 0.42
LCK P06239 1/20 0.42
FYN P06241 1/20 0.42
ADORA3 P0DMS8 1/20 0.42
ALOX15 P16050 1/20 0.42
PTGS1 P23219 1/20 0.42
HTR2A P28223 1/20 0.42
PTGS2 P35354 1/20 0.42
RECQL P46063 1/20 0.42
SLC7A5 Q01650 1/20 0.42
HIF1A Q16665 1/20 0.42
HSD17B10 Q99714 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1666599 0.86 SLC7A5 (0.58) KDM4EUSP2EGFRLCKFYN
SCHEMBL1666513 0.81 SLC7A5 (0.56) LTA4HFFAR1MMP12MMP13KDM4E
SCHEMBL1666512 0.81 SLC1A5 (0.57) SLC1A5LTA4HFFAR1
SCHEMBL3424970 0.79 FFAR1 (0.71) FFAR1
Homophenylalanine SCHEMBL44311 0.77 ALPI (0.64) PTGS1SLC7A5GRIK1GRIA1GRIA2
Homophenylalanine SCHEMBL130567 0.77 ALPI (0.64) PTGS1SLC7A5GRIK1GRIA1GRIA2
Homophenylalanine SCHEMBL1078733 0.77 ALPI (0.64) PTGS1SLC7A5GRIK1GRIA1GRIA2
Homophenylalanine SCHEMBL44312 0.77 ALPI (0.64) PTGS1SLC7A5GRIK1GRIA1GRIA2
SCHEMBL5355497 0.76 LTA4H (0.56) LTA4HFFAR1MMP12MMP13TDP1
SCHEMBL2349792 0.76 FFAR1 (0.58) FFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11118011-B2 Biocompatible polymers for medical devices RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2021-09-14 US disclosed
EP-3461855-B1 BIOCOMPATIBLE POLYMERS FOR MEDICAL DEVICES UNIV RUTGERS (US) 2020-05-27 EP disclosed
US-20190185624-A1 BIOCOMPATIBLE POLYMERS FOR MEDICAL DEVICES RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY 2019-06-20 US disclosed
EP-3461855-A1 BIOCOMPATIBLE POLYMERS FOR MEDICAL DEVICES Rutgers, The State University of New Jersey (US) 2019-04-03 EP disclosed
US-10202490-B2 Biocompatible polymers for medical devices RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2019-02-12 US disclosed
EP-2486081-B1 BIOCOMPATIBLE POLYMERS FOR MEDIAL DEVICES UNIV RUTGERS (US) 2018-12-05 EP disclosed
US-20170158819-A1 BIOCOMPATIBLE POLYMERS FOR MEDICAL DEVICES RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY 2017-06-08 US disclosed
US-9605112-B2 Biocompatible polymers for medical devices RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2017-03-28 US disclosed
US-20120226013-A1 BIOCOMPATIBLE POLYMERS FOR MEDIAL DEVICES RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2012-09-06 US disclosed
EP-2486081-A1 BIOCOMPATIBLE POLYMERS FOR MEDIAL DEVICES Rutgers, The State University of New Jersey (US) 2012-08-15 EP disclosed
WO-2011044567-A1 BIOCOMPATIBLE POLYMERS FOR MEDIAL DEVICES RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2011-04-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120226013-A1 BIOCOMPATIBLE POLYMERS FOR MEDIAL DEVICES MATR3, MIF, BMP2 SLC1A5 3187/4885LTA4H 1151/4885FFAR1 328/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.