Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 6/20 | 0.52 |
| ▸ | TSHR | P16473 | 6/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA7 | P43166 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | CA6 | P23280 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL273483 | 0.83 | NR4A1 (0.61) | CYP3A4TSHRALDH1A1MAPK1GAA | |
| SCHEMBL10915696 | 0.80 | HSP90AA1 (0.48) | CYP3A4TSHRALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL922966 | 0.79 | ALDH1A1 (0.57) | CYP3A4TSHRALDH1A1MAPK1GAA | |
| Hydrochloric Acid SCHEMBL6235407 | 0.77 | ALDH1A1 (0.61) | CYP3A4TSHRALDH1A1MAPK1GAA | |
| SCHEMBL7192417 | 0.76 | MAOA (0.59) | CYP3A4TSHRALDH1A1MAPK1GAA | |
| SCHEMBL10927256 | 0.74 | CA2 (0.50) | CYP3A4TSHRALDH1A1MAPK1GAA | |
| SCHEMBL1876235 | 0.74 | KMT2A (0.59) | CYP3A4TSHRALDH1A1MAPK1HPGD | |
| SCHEMBL1351195 | 0.74 | CYP3A4 (0.45) | CYP3A4TSHRALDH1A1MAPK1GAA | |
| SCHEMBL2944833 | 0.74 | CYP3A4 (0.45) | CYP3A4TSHRALDH1A1MAPK1GAA | |
| SCHEMBL10895459 | 0.74 | CYP3A4 (0.46) | CYP3A4TSHRALDH1A1MAPK1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015057963-A1 | FGFR4 INHIBITORS | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2015-04-23 | — | — | WO | disclosed |