SCHEMBL1666602

SCHEMBL1666602

NC(Cc1ccccc1Oc1ccc(O)cc1)C(=O)O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PCNA P12004 1/20 0.53
SLC1A5 Q15758 4/20 0.53
PPARA Q07869 1/20 0.52
SLC7A5 Q01650 2/20 0.51
NOS3 P29474 2/20 0.47
NOS1 P29475 2/20 0.47
NOS2 P35228 2/20 0.47
KMT2A Q03164 3/20 0.46
MEN1 O00255 2/20 0.46
HSP90AA1 P07900 1/20 0.46
HSP90AB1 P08238 1/20 0.46
LTA4H P09960 1/20 0.46
PLA2G2A P14555 1/20 0.46
ALPI P09923 1/20 0.46
PKM P14618 1/20 0.46
PTGS1 P23219 1/20 0.46
XIAP P98170 1/20 0.46
KDM4E B2RXH2 2/20 0.46
LMNA P02545 2/20 0.46
MAPT P10636 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3621544 0.91 PPARA (0.57) SLC1A5PPARASLC7A5NOS3NOS1
SCHEMBL1666512 0.86 SLC1A5 (0.57) PCNASLC1A5PPARALTA4HFFAR1
SCHEMBL1666604 0.84 CAMK2A (0.63) PCNAPPARASLC7A5NOS3NOS1
SCHEMBL7276739 0.80 PCNA (0.50) PCNASLC1A5PPARASLC7A5KMT2A
SCHEMBL836729 0.80 PCNA (0.56) PCNASLC7A5KMT2AMEN1PKM
SCHEMBL155235 0.77 NOS3 (0.55) SLC1A5SLC7A5NOS3NOS1NOS2
SCHEMBL155234 0.77 NOS3 (0.55) SLC1A5SLC7A5NOS3NOS1NOS2
SCHEMBL285217 0.77 SLC7A5 (0.80) PCNASLC7A5KMT2AMEN1ALPI
SCHEMBL6061862 0.77 GABRA1 (0.47) PPARAKMT2AMEN1LTA4HHTR2A
SCHEMBL29750308 0.77 NOS3 (0.55) SLC1A5SLC7A5NOS3NOS1NOS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11118011-B2 Biocompatible polymers for medical devices RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2021-09-14 US disclosed
EP-3461855-B1 BIOCOMPATIBLE POLYMERS FOR MEDICAL DEVICES UNIV RUTGERS (US) 2020-05-27 EP disclosed
US-20190185624-A1 BIOCOMPATIBLE POLYMERS FOR MEDICAL DEVICES RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY 2019-06-20 US disclosed
EP-3461855-A1 BIOCOMPATIBLE POLYMERS FOR MEDICAL DEVICES Rutgers, The State University of New Jersey (US) 2019-04-03 EP disclosed
US-10202490-B2 Biocompatible polymers for medical devices RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2019-02-12 US disclosed
EP-2486081-B1 BIOCOMPATIBLE POLYMERS FOR MEDIAL DEVICES UNIV RUTGERS (US) 2018-12-05 EP disclosed
US-20170158819-A1 BIOCOMPATIBLE POLYMERS FOR MEDICAL DEVICES RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY 2017-06-08 US disclosed
US-9605112-B2 Biocompatible polymers for medical devices RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2017-03-28 US disclosed
US-20120226013-A1 BIOCOMPATIBLE POLYMERS FOR MEDIAL DEVICES RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2012-09-06 US disclosed
EP-2486081-A1 BIOCOMPATIBLE POLYMERS FOR MEDIAL DEVICES Rutgers, The State University of New Jersey (US) 2012-08-15 EP disclosed
WO-2011044567-A1 BIOCOMPATIBLE POLYMERS FOR MEDIAL DEVICES RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2011-04-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120226013-A1 BIOCOMPATIBLE POLYMERS FOR MEDIAL DEVICES MATR3, MIF, BMP2 PCNA 187/4885SLC1A5 3187/4885PPARA 322/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.