SCHEMBL836729

SCHEMBL836729

NC(Cc1ccc(Oc2ccc(O)cc2)c(I)c1I)C(=O)O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PCNA P12004 2/20 0.56
KMT2A Q03164 7/20 0.48
MEN1 O00255 6/20 0.48
BLM P54132 3/20 0.48
PPARG P37231 3/20 0.48
NR1I2 O75469 2/20 0.48
AGTR2 P50052 1/20 0.48
SLC7A5 Q01650 1/20 0.48
LMNA P02545 6/20 0.43
HSD17B10 Q99714 4/20 0.43
NPSR1 Q6W5P4 3/20 0.43
ALDH1A1 P00352 3/20 0.43
CYP3A4 P08684 3/20 0.43
MAPT P10636 3/20 0.43
ALOX15 P16050 3/20 0.43
ADORA3 P0DMS8 3/20 0.43
TSHR P16473 2/20 0.43
KDM4E B2RXH2 2/20 0.43
NFKB1 P19838 2/20 0.43
PMP22 Q01453 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5574192 0.85 KMT2A (0.52) PCNAKMT2AMEN1BLMPPARG
SCHEMBL230513 0.85 KMT2A (0.52) PCNAKMT2AMEN1BLMPPARG
SCHEMBL282065 0.85 KMT2A (0.52) PCNAKMT2AMEN1BLMPPARG
SCHEMBL1274573 0.84 THRB (0.45) PCNAKMT2AMEN1BLMPPARG
SCHEMBL1742705 0.84 THRB (0.45) PCNAKMT2AMEN1BLMPPARG
SCHEMBL6350388 0.84 KMT2A (0.51) PCNAKMT2AMEN1BLMPPARG
SCHEMBL7276739 0.82 PCNA (0.50) PCNAKMT2AMEN1BLMPPARG
SCHEMBL188397 0.81 PCNA (0.66) PCNAKMT2AMEN1BLMPPARG
SCHEMBL30693721 0.81 PCNA (0.66) PCNAKMT2AMEN1BLMPPARG
SCHEMBL1666602 0.80 PCNA (0.53) PCNAKMT2AMEN1BLMSLC7A5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 379 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4684002-A2 THYROCYTES AND USES THEREOF Lifenet Health (US) 2026-01-28 EP claimed
US-20250345488-A1 CROSSLINKED HYDROGELS WITH ENHANCED RADIOPACITY FOR MEDICAL APPLICATIONS BOSTON SCIENTIFIC SCIMED, INC. (US) 2025-11-13 US claimed
CN-120121693-A Identification of thyroid hormones using reactive heterogeneous nanopores 南京大学 2025-06-10 CN claimed
WO-2024197069-A2 THYROCYTES AND USES THEREOF LIFENET HEALTH (US) 2024-09-26 WO claimed
CN-117554536-B Simultaneous analysis method for 15 thyroid hormones in environmental water sample 北京林业大学 2024-03-19 CN claimed
CN-117554536-A Simultaneous analysis method for 15 thyroid hormones in environmental water sample 北京林业大学 2024-02-13 CN claimed
CN-114813988-B Method for simultaneously extracting and detecting thyroid hormone and steroid hormone in hair 东南大学 2023-12-29 CN claimed
CN-116699150-A Biosensing analysis method for detecting thyroid hormone binding activity in water sample 清华大学 2023-09-05 CN claimed
CN-114813988-A Method for simultaneously extracting and detecting thyroid hormone and steroid hormone in hair 东南大学 2022-07-29 CN claimed
US-9890116-B2 Process for the preparation of a sulfated derivative of 3,5-diiodo-O-[3-iodophenyl]-L-tyrosine BRACCO IMAGING S.P.A. (IT) 2018-02-13 US claimed
EP-0732920-A1 THERAPEUTIC AGENTS CONTAINING THYROID HORMONES Knoll AG (DE) 1996-09-25 EP claimed
WO-1995020953-A1 THERAPEUTIC AGENTS CONTAINING THYROID HORMONES KNOLL AG (DE) 1995-08-10 WO claimed
WO-1995020954-A1 TABLETS CONTAINING THYROID HORMONES KNOLL AG (DE) 1995-08-10 WO claimed
EP-0357725-B1 PHARMACEUTICAL COMPOSITION FOR TREATMENT OF LUNG OBSTRUCTIONS SMITH, Ulf Per Gustav (SE) 1992-04-15 EP claimed
EP-0073865-B1 DERIVATIVES OF IODOTHYRONINE COMPOUNDS AND THEIR USE IN AN ASSAY FOR THE FREE IODOTHYRONINE COMPOUNDS AMERSHAM INTERNATIONAL plc (GB) 1986-01-29 EP claimed
EP-0093653-B1 PROCESS FOR THE PREPARATION OF IODO-THYRONINES AND IODO-THYROACETIC ACIDS BY ELECTROCHEMICAL REDUCTION AT A CONTROLLED POTENTIAL SPIRAL Société à responsabilité limitée dite : (FR) 1985-07-10 EP claimed
US-4490221-A Process for preparing iodothyronines and iodothyroacetic acids by electrochemical reduction at controlled potential SPIRAL SOCIETE A RESPONSABILITE LIMITEE DITE (FR) 1984-12-25 US claimed
US-4426453-A Derivatives of iodothyronine compounds and their use in an assay for the free iodothyronine compounds AMERSHAM INTERNATIONAL LIMITED (GB) 1984-01-17 US claimed
EP-0093653-A1 Process for the preparation of iodo-thyronines and iodo-thyroacetic acids by electrochemical reduction at a controlled potential SPIRAL Société à responsabilité limitée dite : (FR) 1983-11-09 EP claimed
EP-0073865-A1 Derivatives of iodothyronine compounds and their use in an assay for the free iodothyronine compounds AMERSHAM INTERNATIONAL plc (GB) 1983-03-16 EP claimed