Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16667514 | 0.77 | UCHL1 (0.39) | DRD1 | |
| SCHEMBL298657 | 0.71 | KCNJ1 (0.38) | DRD1 | |
| SCHEMBL7406722 | 0.70 | DRD1 (0.41) | DRD1 | |
| SCHEMBL23148192 | 0.70 | DRD1 (0.35) | DRD1 | |
| SCHEMBL286681 | 0.69 | DRD1 (0.39) | DRD1 | |
| SCHEMBL2891099 | 0.69 | KCNJ1 (0.40) | DRD1 | |
| SCHEMBL2733021 | 0.69 | TERT (0.41) | — | |
| SCHEMBL299486 | 0.69 | KCNJ1 (0.38) | DRD1 | |
| SCHEMBL19812961 | 0.68 | DRD1 (0.37) | DRD1 | |
| SCHEMBL20700121 | 0.68 | ALDH1A1 (0.48) | DRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2632464-B1 | INHIBITORS OF THE RENAL OUTER MEDULLARY POTASSIUM CHANNEL | MERCK SHARP & DOHME (US) | 2015-04-29 | — | — | EP | disclosed |