Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.33 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.32 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.32 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19812961 | 0.84 | DRD1 (0.37) | DRD1ALDH1A1LMNAKMT2AGID4 | |
| SCHEMBL29981118 | 0.79 | UCHL1 (0.35) | DRD1ALDH1A1PTGDRADRA2AADRA2B | |
| SCHEMBL29980839 | 0.79 | UCHL1 (0.35) | DRD1ALDH1A1PTGDRADRA2AADRA2B | |
| SCHEMBL29981159 | 0.79 | UCHL1 (0.35) | DRD1ALDH1A1PTGDRADRA2AADRA2B | |
| SCHEMBL19821177 | 0.79 | UCHL1 (0.35) | DRD1ALDH1A1PTGDRADRA2AADRA2B | |
| SCHEMBL20703964 | 0.79 | ADRA2A (0.35) | DRD1ALDH1A1GID4PTGDRTSHR | |
| SCHEMBL7406722 | 0.77 | DRD1 (0.41) | DRD1ALDH1A1LMNAKMT2AGID4 | |
| SCHEMBL286681 | 0.76 | DRD1 (0.39) | DRD1ALDH1A1GID4HTR2C | |
| SCHEMBL2039585 | 0.75 | LMNA (0.30) | ALDH1A1LMNAKMT2AMEN1TSHR | |
| SCHEMBL2034863 | 0.75 | TAAR1 (0.51) | LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11491133-B2 | Heteroaryl-isochroman compounds and uses thereof | SUNOVION PHARMACEUTICALS INC. (US) | 2022-11-08 | — | — | US | disclosed |
| US-20210093606-A1 | COMPOUNDS AND USES THEREOF | SUNOVION PHARMACEUTICALS INC. (US) | 2021-04-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210093606-A1 | COMPOUNDS AND USES THEREOF | PYGB, NLN, MAOB | DRD1 1110/4885ALDH1A1 178/4885LMNA 1614/4885 |
| US-11491133-B2 | Heteroaryl-isochroman compounds and uses thereof | GRIN2C, INA, SDHA | DRD1 1458/4885ALDH1A1 704/4885LMNA 2370/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.