SCHEMBL16668783

SCHEMBL16668783

O=C1Nc2cc(Br)ccc2C1=C1C(=O)Nc2cc(Br)ccc21

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TGM2 P21980 3/20 0.55
CES1 P23141 2/20 0.55
TDP2 O95551 1/20 0.46
S100A4 P26447 1/20 0.45
KDR P35968 1/20 0.44
CMA1 P23946 1/20 0.44
AHR P35869 1/20 0.44
CA1 P00915 2/20 0.42
CA2 P00918 2/20 0.42
CA4 P22748 2/20 0.42
CA7 P43166 2/20 0.42
CA9 Q16790 2/20 0.42
PARP10 Q53GL7 1/20 0.42
PARP11 Q9NR21 1/20 0.42
MAOA P21397 2/20 0.41
MAOB P27338 2/20 0.41
LRRK2 Q5S007 2/20 0.41
CA12 O43570 1/20 0.41
AGTR1 P30556 1/20 0.41
PIM1 P11309 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13058804 1.00 TGM2 (0.55) TGM2CES1TDP2S100A4KDR
SCHEMBL19931150 0.87 TGM2 (0.59) TGM2CES1TDP2S100A4KDR
SCHEMBL8557 0.83 CES1 (0.71) TGM2CES1TDP2S100A4KDR
SCHEMBL31107465 0.80 TGM2 (0.52) TGM2CES1TDP2S100A4KDR
Nitrogen SCHEMBL29155979 0.80 CES1 (0.67) TGM2CES1TDP2S100A4KDR
SCHEMBL22300036 0.79 MAOA (0.49) TGM2CES1MAOAMAOBLRRK2
SCHEMBL21479904 0.79 MAOA (0.49) TGM2CES1MAOAMAOBLRRK2
SCHEMBL15762686 0.78 CES1 (0.46) TGM2CES1S100A4KDRMAOA
SCHEMBL5316821 0.77 TGM2 (0.39) TGM2CES1TDP2KDRCMA1
SCHEMBL10039266 0.77 TGM2 (0.42) TGM2CES1KDRMAOAMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150114467-A1 DONOR-ACCEPTOR ALTERNATING CONJUGATED POLYMER AND SOLAR CELL DEVICE MANUFACTURED BY USING THE SAME NATIONAL TAIWAN UNIVERSITY (TW) 2015-04-30 US disclosed