Known targets — ChEMBL curated mechanism
ABL1BMXBRAFBTKCHRNA4CHRNB2CSNK1EEGFRERBB2F10FLT1FLT3FLT4IGF1RINSRITKJAK3KDRKITOPRM1PARP1PARP2PDGFRBPIK3CDRAF1RETSLC18A2TECTXKdacAdacBdacCftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16668777 | 0.88 | — | — | |
| Trifluoromethanesulfonic Acid SCHEMBL16669075 | 0.88 | — | — | |
| Bromide SCHEMBL16669173 | 0.87 | — | — | |
| Hydrochloric Acid SCHEMBL16668836 | 0.87 | — | — | |
| Iodide SCHEMBL16668820 | 0.87 | — | — | |
| Hydrochloric Acid SCHEMBL16669271 | 0.78 | — | — | |
| Hydrochloric Acid SCHEMBL16669144 | 0.77 | — | — | |
| Hydrochloric Acid SCHEMBL16668660 | 0.77 | — | — | |
| SCHEMBL16669130 | 0.76 | CA12 (0.32) | L3MBTL1CA12CA2LMNACA9 | |
| Hydrochloric Acid SCHEMBL16668892 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3063184-B1 | ASYMMETRIC CATALYSTS FOR OLEFIN POLYMERISATION | EXXONMOBIL CHEMICAL PATENTS INC (US) | 2017-11-29 | — | — | EP | disclosed |
| EP-3063184-A1 | ASYMMETRIC POLYPROPYLENE CATALYSTS | ExxonMobil Chemical Patents Inc. (US) | 2016-09-07 | — | — | EP | disclosed |
| US-9266910-B2 | Asymmetric polypropylene catalysts | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2016-02-23 | — | — | US | disclosed |
| WO-2015065681-A1 | ASYMMETRIC POLYPROPYLENE CATALYSTS | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2015-05-07 | — | — | WO | disclosed |
| US-20150119539-A1 | Asymmetric Polypropylene Catalysts | EXXONMOBIL CHEMICAL PATENTS INC. | 2015-04-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150119539-A1 | Asymmetric Polypropylene Catalysts | PIN1, PPIF, PPOX | L3MBTL1 1807/4885CA12 3736/4885CA2 4706/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.