Hydrochloric Acid

Hydrochloric Acid

SCHEMBL16669342

C[Si](C)=[Hf+2](C1C(C2CC2)=Cc2c(-c3ccccc3)cccc21)C1C(C2CC2)=Cc2c(-c3ccccc3)cccc21.[Cl-].[Cl-]

nearest known ligand 0.34

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CHRNB2 P17787 1/20 0.33
CHRNA4 P43681 1/20 0.33
ADRA2A P08913 2/20 0.32
ADRA1D P25100 1/20 0.32
ADRA1A P35348 1/20 0.32
BRD4 O60885 1/20 0.32
PDK2 Q15119 1/20 0.31
PDK4 Q16654 1/20 0.31
USP30 Q70CQ3 1/20 0.30
ADRA2B P18089 1/20 0.30
ADRA2C P18825 1/20 0.30
HTR1A P08908 1/20 0.30
HTR7 P34969 1/20 0.30
HTR2B P41595 1/20 0.30
TMEM97 Q5BJF2 1/20 0.30
SIGMAR1 Q99720 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL6056145 0.94 PDK2 (0.31) PDK2PDK4USP30
Hydrochloric Acid SCHEMBL16393617 0.87 BRD4 (0.33) BRD4
Hydrochloric Acid SCHEMBL16393653 0.84 HTR1A (0.32) BRD4HTR1AHTR7
Hydrochloric Acid SCHEMBL1201260 0.81 PDCD1 (0.31) CHRNB2CHRNA4
Hydrochloric Acid SCHEMBL969085 0.81 PDCD1 (0.31) CHRNB2CHRNA4
Hydrochloric Acid SCHEMBL7926684 0.78
Hydrochloric Acid SCHEMBL31126393 0.78
Hydrochloric Acid SCHEMBL7217384 0.78
Hydrochloric Acid SCHEMBL16393580 0.77 CHRNB2 (0.33) CHRNB2CHRNA4ADRA2ABRD4PDK2
Hydrochloric Acid SCHEMBL31425736 0.77 CHRNB2 (0.33) CHRNB2CHRNA4ADRA2ABRD4PDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11192961-B2 Production of heterophasic polymers in gas or slurry phase EXXONMOBIL CHEMICAL PATENTS INC. (US) 2021-12-07 US claimed
US-20200223950-A1 Production of Heterophasic Polymers in Gas or Slurry Phase EXXONMOBIL CHEMICAL PATENTS INC. 2020-07-16 US claimed
US-10570219-B2 Production of heterophasic polymers in gas or slurry phase EXXONMOBIL CHEMICAL PATENTS INC. (US) 2020-02-25 US claimed
US-10280233-B2 Catalyst systems and methods of making and using the same EXXONMOBIL CHEMICAL PATENTS INC. (US) 2019-05-07 US claimed
US-9920176-B2 Single site catalyst supportation EXXONMOBIL CHEMICAL PATENTS INC. (US) 2018-03-20 US claimed
US-9725537-B2 High activity catalyst supportation EXXONMOBIL CHEMICAL PATENTS INC. (US) 2017-08-08 US claimed
US-12304981-B2 Polymerization using a spiral heat exchanger ExxonMobil Engineering & Technology Company (US) 2025-05-20 US disclosed
US-20220162348-A1 Polymerization Using a Spiral Heat Exchanger EXXONMOBIL CHEMICAL PATENTS INC (US) 2022-05-26 US disclosed
US-11279775-B2 Polymerization using a spiral heat exchanger EXXONMOBIL CHEMICAL PATENTS INC. (US) 2022-03-22 US disclosed
US-11192961-B2 Production of heterophasic polymers in gas or slurry phase EXXONMOBIL CHEMICAL PATENTS INC. (US) 2021-12-07 US disclosed
EP-3885373-A1 PRODUCTION OF HETEROPHASIC POLYMERS IN GAS OR SLURRY PHASE ExxonMobil Chemical Patents Inc. (US) 2021-09-29 EP disclosed
US-11034827-B2 Heterophasic copolymers and polymerization methods EXXONMOBIL CHEMICAL PATENTS INC. (US) 2021-06-15 US disclosed
EP-3303422-B1 PRODUCTION OF HETEROPHASIC POLYMERS IN GAS OR SLURRY PHASE EXXONMOBIL CHEMICAL PATENTS INC (US) 2021-03-17 EP disclosed
WO-2016195868-A1 SINGLE SITE CATALYST SUPPORTATION EXXONMOBIL CHEMICAL PATENTS INC. (US) 2016-12-08 WO disclosed
WO-2016195876-A1 SILICA SUPPORTS WITH HIGH ALUMINOXANE LOADING CAPABILITY EXXONMOBIL CHEMICAL PATENTS INC. (US) 2016-12-08 WO disclosed
WO-2016195866-A1 HIGH ACTIVITY CATALYST SUPPORTATION EXXONMOBIL CHEMICAL PATENTS INC. (US) 2016-12-08 WO disclosed
US-20160137763-A1 Processes Using Staged Hydrogen Addition EXXONMOBIL CHEMICAL PATENTS INC. 2016-05-19 US disclosed
US-9279024-B2 Processes using staged hydrogen addition EXXONMOBIL CHEMICAL PATENTS INC. (US) 2016-03-08 US disclosed
WO-2015065676-A1 PROCESSES USING STAGED HYDROGEN ADDITION EXXONMOBIL CHEMICAL PATENTS INC. (US) 2015-05-07 WO disclosed
US-20150119537-A1 Processes Using Staged Hydrogen Addition EXXONMOBIL CHEMICAL PATENTS INC. 2015-04-30 US disclosed