Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.31 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL16669342 | 0.94 | CHRNB2 (0.33) | PDK2PDK4USP30 | |
| Hydrochloric Acid SCHEMBL969085 | 0.89 | PDCD1 (0.31) | — | |
| Hydrochloric Acid SCHEMBL1201260 | 0.89 | PDCD1 (0.31) | — | |
| Hydrochloric Acid SCHEMBL6056246 | 0.83 | — | — | |
| Hydrochloric Acid SCHEMBL16393617 | 0.82 | BRD4 (0.33) | — | |
| Hydrochloric Acid SCHEMBL16393653 | 0.79 | HTR1A (0.32) | — | |
| Hydrochloric Acid SCHEMBL16393749 | 0.79 | HTR2C (0.31) | — | |
| Hydrochloric Acid SCHEMBL7935671 | 0.78 | — | — | |
| Hydrochloric Acid SCHEMBL7935410 | 0.77 | — | — | |
| Hydrochloric Acid SCHEMBL8465331 | 0.75 | DRD2 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6995279-B2 | Metallocene compounds, processes for the production of olefin polymers using catalysts containing the compounds, and olefin polymers produced by the processes | CHISSO CORPORATION (JP) | 2006-02-07 | — | — | US | disclosed |
| US-20040127731-A1 | Metallocene compounds, processes for the production of olefin polymers using catalysts containing the compounds, and olefin polymers produced by the processes | CHISSO CORPORATION (JP) | 2004-07-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040127731-A1 | Metallocene compounds, processes for the production of olefin polymers using catalysts containing the compounds, and olefin polymers produced by the processes | MLX, ZYX, YBX1 | PDK2 956/4885PDK4 639/4885USP30 3579/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.