4-Aminophenol

4-Aminophenol

SCHEMBL16670828

CCCC(=O)O.Nc1ccc(O)cc1

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.52
CYP3A4 P08684 2/20 0.52
FFAR3 O14843 1/20 0.52
HDAC3 O15379 1/20 0.52
HDAC1 Q13547 1/20 0.52
HDAC2 Q92769 1/20 0.52
HDAC8 Q9BY41 1/20 0.52
CA3 P07451 1/20 0.52
THRB P10828 1/20 0.52
ALOX15 P16050 1/20 0.52
CA6 P23280 1/20 0.52
CASP1 P29466 1/20 0.52
HIF1A Q16665 1/20 0.52
HSD17B10 Q99714 1/20 0.52
CA14 Q9ULX7 1/20 0.52
HSD17B3 P37058 8/20 0.52
ESR1 P03372 3/20 0.46
ESR2 Q92731 3/20 0.46
CYP19A1 P11511 2/20 0.46
CYP1A1 P04798 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydroquinone SCHEMBL10941615 0.89 FFAR3 (0.65) ALDH1A1CYP3A4FFAR3HDAC3HDAC1
Octanoic Acid SCHEMBL27562486 0.85 GPR84 (0.59) ALDH1A1ALOX15HSD17B10HSD17B3ESR1
Dodecanoate SCHEMBL27709113 0.85 GPR84 (0.59) ALDH1A1ALOX15HSD17B10HSD17B3ESR1
Stearic Acid SCHEMBL299703 0.85 GPR84 (0.59) ALDH1A1ALOX15HSD17B10HSD17B3ESR1
Glutarate SCHEMBL10600593 0.83 ALDH1A1 (0.56) ALDH1A1CYP3A4HDAC3HDAC1HDAC2
Aniline SCHEMBL7998555 0.83 HDAC3 (0.56) ALDH1A1FFAR3HDAC3HDAC1HDAC2
Butyric Acid SCHEMBL11247238 0.82 FFAR3 (0.50) ALDH1A1CYP3A4FFAR3HDAC3HDAC1
Butyric Acid SCHEMBL4774927 0.82 FFAR3 (0.50) ALDH1A1CYP3A4FFAR3HDAC3HDAC1
4-Chloroaniline SCHEMBL28415706 0.82 FFAR3 (0.50) ALDH1A1CYP3A4FFAR3HDAC3HDAC1
Aniline SCHEMBL29152188 0.82 HDAC3 (0.54) ALDH1A1FFAR3HDAC3HDAC1HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015059040-A1 METHOD FOR DETECTING AND QUANTIFYING A SINGLE-STRANDED TARGET NUCLEIC ACID SIEMENS AKTIENGESELLSCHAFT (DE) 2015-04-30 WO disclosed