SCHEMBL1667155

SCHEMBL1667155

CC(=O)c1ccc(C)c(C)c1C(C)=O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.38
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
THRB P10828 2/20 0.38
SMN1; SMN2 Q16637 4/20 0.37
CSNK1A1 P48729 1/20 0.35
CSNK1D P48730 1/20 0.35
CLK2 P49760 1/20 0.35
CSNK1G1 Q9HCP0 1/20 0.35
BRPF1 P55201 1/20 0.35
PKM P14618 1/20 0.35
CYP3A4 P08684 4/20 0.34
CYP1A2 P05177 1/20 0.34
HPGD P15428 3/20 0.34
ALDH1A1 P00352 2/20 0.34
MAPK1 P28482 2/20 0.34
NCEH1 Q6PIU2 1/20 0.34
PPARG P37231 1/20 0.34
TDP1 Q9NUW8 2/20 0.33
L3MBTL1 Q9Y468 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methane SCHEMBL28696311 0.98 MAPT (0.37) MAPTNPC1RAB9ATHRBSMN1; SMN2
SCHEMBL1667194 0.84 THRB (0.39) MAPTNPC1RAB9ATHRBSMN1; SMN2
SCHEMBL3742961 0.83 THRB (0.42) MAPTNPC1RAB9ATHRBSMN1; SMN2
SCHEMBL7177477 0.81 SMN1; SMN2 (0.39) MAPTSMN1; SMN2CSNK1A1CSNK1DCLK2
SCHEMBL1665864 0.80 THRB (0.48) MAPTTHRBSMN1; SMN2CYP3A4CYP1A2
SCHEMBL11405036 0.77 SMN1; SMN2 (0.37) MAPTNPC1RAB9ASMN1; SMN2BRPF1
SCHEMBL32678438 0.77 MAPT (0.47) MAPTSMN1; SMN2BRPF1CYP3A4HPGD
SCHEMBL6667388 0.77 MAPT (0.47) MAPTSMN1; SMN2BRPF1CYP3A4HPGD
SCHEMBL15657985 0.77 MAPT (0.31) MAPTNPC1RAB9ASMN1; SMN2CYP3A4
SCHEMBL23112646 0.76 HPGD (0.41) MAPTSMN1; SMN2BRPF1CYP3A4HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114106338-A Silicon aryne resin with p-diacetylene diphenylmethane structure and composite material and preparation method thereof 华东理工大学 2022-03-01 CN disclosed
EP-1830228-B1 COMPOUND FOR RESIST AND RADIATION-SENSITIVE COMPOSITION MITSUBISHI GAS CHEMICAL CO (JP) 2015-08-05 EP disclosed
EP-2808736-A2 Compound for resist and radiation-sensitive composition MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2014-12-03 EP disclosed
US-8802353-B2 Compound for resist and radiation-sensitive composition specification MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2014-08-12 US disclosed
EP-2662727-A2 Compound for resist and radiation-sensitive composition MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2013-11-13 EP disclosed
US-8350096-B2 Compound for resist and radiation-sensitive composition MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2013-01-08 US disclosed
US-20130004896-A1 COMPOUND FOR RESIST AND RADIATION-SENSITIVE COMPOSITION SPECIFICATION ECHIGO MASATOSHI (JP) 2013-01-03 US disclosed
US-20110165516-A1 COMPOUND FOR RESIST AND RADIATION-SENSITIVE COMPOSITION ECHIGO MASATOSHI 2011-07-07 US disclosed
CN-101088046-B Compound for resist and radiation-sensitive composition MITSUBISHI GAS CHEMICAL CO 2011-05-25 CN disclosed
US-7919223-B2 Polyphenol compound synthesized by condensation between aromatic ketone or aldehyde and a phenol; acid-amplified, non-polymeric resist; highly sensitive to KrF excimer lasers, extreme ultraviolet rays, electron beams, X-rays; resist patterns with high resolution, high heat, etch resistance MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2011-04-05 US disclosed
US-20080113294-A1 Compound for Resist and Radiation-Sensitive Composition MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2008-05-15 US disclosed
CN-101088046-A Compound for resist and radiation-sensitive composition MITSUBISHI GAS CHEMICAL CO (JP) 2007-12-12 CN disclosed
EP-1830228-A1 COMPOUND FOR RESIST AND RADIATION-SENSITIVE COMPOSITION MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2007-09-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110165516-A1 COMPOUND FOR RESIST AND RADIATION-SENSITIVE COMPOSITION XRCC6, XRCC5, KISS1R MAPT 1377/4885NPC1 3988/4885RAB9A 1869/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.