SCHEMBL7177477

SCHEMBL7177477

CC(=O)c1ccc(C)c(C)c1C

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 5/20 0.39
BRPF1 P55201 1/20 0.37
ALDH1A1 P00352 4/20 0.36
HPGD P15428 3/20 0.36
MAPK1 P28482 2/20 0.36
CYP3A4 P08684 1/20 0.36
PPARG P37231 1/20 0.36
MAPT P10636 2/20 0.35
TDP1 Q9NUW8 2/20 0.35
L3MBTL1 Q9Y468 2/20 0.35
GAA P10253 2/20 0.35
ALOX15 P16050 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
TDP2 O95551 1/20 0.34
NSD2 O96028 1/20 0.34
HSP90AA1 P07900 1/20 0.34
PAX8 Q06710 1/20 0.34
HTT P42858 2/20 0.34
KDM4E B2RXH2 3/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8732527 0.82 TDP2 (0.36) SMN1; SMN2ALDH1A1HPGDCYP3A4MAPT
SCHEMBL14514161 0.82 TDP1 (0.37) ALDH1A1HPGDCYP3A4MAPTTDP1
SCHEMBL1667155 0.81 MAPT (0.38) SMN1; SMN2BRPF1ALDH1A1HPGDMAPK1
SCHEMBL32678438 0.81 MAPT (0.47) SMN1; SMN2BRPF1ALDH1A1HPGDMAPK1
SCHEMBL7049791 0.81 ALDH1A1 (0.42) SMN1; SMN2BRPF1ALDH1A1HPGDMAPK1
SCHEMBL11405036 0.81 SMN1; SMN2 (0.37) SMN1; SMN2BRPF1ALDH1A1HPGDMAPK1
SCHEMBL6667388 0.81 MAPT (0.47) SMN1; SMN2BRPF1ALDH1A1HPGDMAPK1
SCHEMBL18486701 0.81 DAO (0.32) ALDH1A1HPGDCYP3A4TDP1CYP2C9
SCHEMBL1259607 0.80 TDP2 (0.34) SMN1; SMN2ALDH1A1HPGDCYP3A4MAPT
SCHEMBL29370019 0.80 CYP1A2 (0.48) ALDH1A1HPGDCYP3A4TDP1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116710500-A Polymer, composition, method for producing polymer, composition for forming film, resist composition, method for forming resist pattern, radiation-sensitive composition, composition for forming underlayer film for lithography, method for producing underlayer film for lithography, method for forming circuit pattern, and composition for forming optical member 三菱瓦斯化学株式会社 2023-09-05 CN disclosed
WO-2022104049-A1 SYNTHESIS OF ARYL 1-(METHOXYMETHYL) VINYL KETONES AND THEIR USE AS INHIBITORS OF MILD STEEL CORROSION SAUDI ARABIAN OIL COMPANY (SA) 2022-05-19 WO disclosed
CN-111182962-B Composition comprising solvent-resistant and heat-resistant capsules 爱克发有限公司 2022-05-17 CN disclosed
US-20220145179-A1 SYNTHESIS OF ARYL 1-(METHOXYMETHYL) VINYL KETONES AND THEIR USE AS INHIBITORS OF MILD STEEL CORROSION SAUDI ARABIAN OIL COMPANY (SA) 2022-05-12 US disclosed
CN-113302223-A Film-forming composition, resist composition, radiation-sensitive composition, method for producing amorphous film, method for forming resist pattern, composition for forming underlayer film for lithography, method for producing underlayer film for lithography, and method for forming circuit pattern 三菱瓦斯化学株式会社 2021-08-24 CN disclosed
CN-113286841-A Polycyclic polyphenol resin and method for producing polycyclic polyphenol resin 三菱瓦斯化学株式会社 2021-08-20 CN disclosed
CN-111182963-A Composition comprising solvent-resistant and heat-resistant capsules 爱克发有限公司 2020-05-19 CN disclosed
CN-111182962-A Composition comprising solvent-resistant and heat-resistant capsules 爱克发有限公司 2020-05-19 CN disclosed
US-10023563-B2 Cyclic compounds substituted by a condensed ring system BASF SE (DE) 2018-07-17 US disclosed
US-9877946-B2 Method for treating, managing, inhibiting, or preventing obesity Research & Business Foundation Sungkyunkwan University (KR) 2018-01-30 US disclosed
US-20170087126-A1 COMPOSITION FOR INDUCING DIFFERENTIATION INTO BEIGE AND BROWN ADIPOCYTES AND METHOD OF INDUCING THE SAME RESEARCH & BUSINESS FOUNDATION SUNGKYUNKWAN UNIVER SITY (KR) 2017-03-30 US disclosed
US-9549908-B2 Composition for inducing differentiation into beige and brown adipocytes and method of inducing the same Research & Business Foundation Sungkyunkwan University, Ltd. (KR) 2017-01-24 US disclosed
US-20160185699-A1 METHOD OF ACYLATING AN AROMATIC COMPOUND DSM IP ASSETS B.V. (NL) 2016-06-30 US disclosed
EP-3016926-A1 METHOD OF ACYLATING AN AROMATIC COMPOUND DSM IP Assets B.V. (NL) 2016-05-11 EP disclosed
US-20150374643-A1 COMPOSITION FOR INDUCING DIFFERENTIATION INTO BEIGE AND BROWN ADIPOCYTES AND METHOD OF INDUCING THE SAME Research & Business Foundation Sungkyunkwan University (KR) 2015-12-31 US disclosed
WO-2015001032-A1 METHOD OF ACYLATING AN AROMATIC COMPOUND DSM IP ASSETS B.V. (NL) 2015-01-08 WO disclosed
US-7429411-B2 Chroman compound, liquid crystal composition including the compound and liquid crystal display element including the liquid crystal composition CHISSO PETROCHEMICAL CORPORATION (JP) 2008-09-30 US disclosed
EP-1349823-A1 PROCESS FOR BASE-PROMOTED CONDENSATION REACTIONS AND BASE REAGENT THEREFOR Crompton Corporation (US) 2003-10-08 EP disclosed
WO-2002055466-A1 PROCESS FOR BASE-PROMOTED CONDENSATION REACTIONS AND BASE REAGENT THEREFOR CROMPTON CORPORATION (US) 2002-07-18 WO disclosed
EP-0328669-A1 CHALCONE DERIVATIVE COMPOUNDS NIPPON OIL AND FATS COMPANY, LIMITED (JP) 1989-08-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170087126-A1 COMPOSITION FOR INDUCING DIFFERENTIATION INTO BEIGE AND BROWN ADIPOCYTES AND METHOD OF INDUCING THE SAME FABP4, PLIN1, PRDM7 SMN1; SMN2 3974/4885BRPF1 68/4885ALDH1A1 593/4885
US-20220145179-A1 SYNTHESIS OF ARYL 1-(METHOXYMETHYL) VINYL KETONES AND THEIR USE AS INHIBITORS OF MILD STEEL CORROSION PAH, CYP2F1, ADH1C SMN1; SMN2 3579/4885BRPF1 2829/4885ALDH1A1 15/4885
US-20150374643-A1 COMPOSITION FOR INDUCING DIFFERENTIATION INTO BEIGE AND BROWN ADIPOCYTES AND METHOD OF INDUCING THE SAME FABP4, PLIN1, PRDM7 SMN1; SMN2 3974/4885BRPF1 68/4885ALDH1A1 593/4885
US-20160185699-A1 METHOD OF ACYLATING AN AROMATIC COMPOUND ARSA, ACR, APEH SMN1; SMN2 3147/4885BRPF1 2932/4885ALDH1A1 2584/4885
US-10023563-B2 Cyclic compounds substituted by a condensed ring system CYCS, DDT, CAT SMN1; SMN2 2126/4885BRPF1 448/4885ALDH1A1 1724/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.