SCHEMBL16673121

SCHEMBL16673121

CCCC(=O)Oc1ccccc1OC(F)(F)F

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
F2R P25116 1/20 0.48
KDM4E B2RXH2 1/20 0.48
MEN1 O00255 1/20 0.48
RECQL P46063 1/20 0.48
KMT2A Q03164 1/20 0.48
ALOX15 P16050 1/20 0.47
RXRA P19793 1/20 0.44
RXRB P28702 1/20 0.44
RXRG P48443 1/20 0.44
LMNA P02545 1/20 0.43
VNN1 O95497 1/20 0.42
PPARG P37231 2/20 0.41
L3MBTL1 Q9Y468 2/20 0.40
ALDH1A1 P00352 1/20 0.40
FFAR4 Q5NUL3 1/20 0.40
EPHX2 P34913 1/20 0.40
KCNK3 O14649 2/20 0.39
KCNK9 Q9NPC2 2/20 0.39
FFAR1 O14842 1/20 0.39
BCL9 O00512 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9312497 0.86 KMT2A (0.59) KDM4EMEN1RECQLKMT2AALOX15
SCHEMBL15548829 0.81 KMT2A (0.54) KDM4EMEN1RECQLKMT2AALOX15
SCHEMBL1997892 0.81 PPARG (0.48) F2RKDM4EMEN1RECQLKMT2A
SCHEMBL15548744 0.80 PTGS2 (0.54) KDM4EMEN1RECQLKMT2AALOX15
SCHEMBL1792324 0.80 L3MBTL1 (0.56) KDM4EMEN1RECQLKMT2AALOX15
SCHEMBL15547682 0.80 KDM4E (0.71) KDM4EMEN1RECQLKMT2AALOX15
SCHEMBL31053826 0.80 L3MBTL1 (0.56) KDM4EMEN1RECQLKMT2AALOX15
SCHEMBL16672735 0.79 PPARG (0.49) F2RRXRARXRBRXRGVNN1
SCHEMBL16672440 0.79 RXRA (0.44) F2RKDM4EMEN1RECQLKMT2A
SCHEMBL16672771 0.79 RXRA (0.41) F2RKDM4EMEN1RECQLKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2869389-B1 NONAQUEOUS ELECTROLYTIC SOLUTION AND NONAQUEOUS ELECTROLYTIC SOLUTION CELL USING SAME MITSUBISHI CHEM CORP (JP) 2019-11-13 EP disclosed
US-10320030-B2 Nonaqueous electrolyte solution and nonaqueous electrolyte battery employing the same MITSUBISHI CHEMICAL CORPORATION (JP) 2019-06-11 US disclosed
US-20150140448-A1 NONAQUEOUS ELECTROLYTE SOLUTION AND NONAQUEOUS ELECTROLYTE BATTERY EMPLOYING THE SAME MITSUBISHI CHEMICAL CORPORATION (JP) 2015-05-21 US disclosed
EP-2869389-A1 NONAQUEOUS ELECTROLYTIC SOLUTION AND NONAQUEOUS ELECTROLYTIC SOLUTION CELL USING SAME Mitsubishi Chemical Corporation (JP) 2015-05-06 EP disclosed
US-20140107135-A1 PYRIMIDINONE INHIBITORS OF LIPOPROTEIN-ASSOCIATED PHOSPHOLIPASE A2 AUSPEX PHARMACEUTICALS, INC. (US) 2014-04-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140107135-A1 PYRIMIDINONE INHIBITORS OF LIPOPROTEIN-ASSOCIATED PHOSPHOLIPASE A2 PLA2G1B, PLA2G4A, PLA2G4B F2R 286/4885KDM4E 3515/4885MEN1 3297/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.