Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | MC4R | P32245 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | CTSG | P08311 | 1/20 | 0.35 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26469162 | 0.79 | SIGMAR1 (0.44) | SIGMAR1MC4RGAAELANELMNA | |
| SCHEMBL4945693 | 0.72 | ALDH1A1 (0.40) | SIGMAR1DRD2DRD4DRD3KDM4E | |
| SCHEMBL6132960 | 0.70 | JAK2 (0.44) | SIGMAR1MC4RGAAELANELMNA | |
| SCHEMBL12626083 | 0.68 | CYP3A4 (0.53) | SIGMAR1POLBALDH1A1 | |
| SCHEMBL18096014 | 0.68 | GAA (0.44) | SIGMAR1MC4RGAAELANECTSG | |
| SCHEMBL17700194 | 0.67 | GAA (0.53) | SIGMAR1MC4RGAAELANELMNA | |
| SCHEMBL2073777 | 0.67 | SIGMAR1 (0.50) | SIGMAR1MC4RGAALMNAPOLB | |
| SCHEMBL2147364 | 0.67 | CYP3A4 (0.56) | SIGMAR1DRD2DRD4DRD3MC4R | |
| SCHEMBL6133048 | 0.67 | MEN1 (0.39) | SIGMAR1MC4RGAAPOLBKDM4E | |
| SCHEMBL12625885 | 0.67 | TSHR (0.51) | SIGMAR1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3066070-B1 | CATALYTIC HYDROGENATION FOR THE PREPARATION OF AMINES FROM AMIDE ACETALS, KETENE-N, O-ACETALS OR ESTERIMIDES | EVONIK DEGUSSA GMBH (DE) | 2019-07-17 | — | — | EP | disclosed |
| EP-3066070-B1 | CATALYTIC HYDROGENATION FOR THE PREPARATION OF AMINES FROM AMIDE ACETALS, KETENE-N, O-ACETALS OR ESTERIMIDES | EVONIK DEGUSSA GMBH (DE) | 2019-07-17 | — | — | EP | disclosed |
| US-9890108-B2 | Catalytic hydrogenation for the preparation of amines from amide acetals, ketene N, O-acetals or ester imides | EVONIK DEGUSSA GMBH (DE) | 2018-02-13 | — | — | US | disclosed |
| US-9890108-B2 | Catalytic hydrogenation for the preparation of amines from amide acetals, ketene N, O-acetals or ester imides | EVONIK DEGUSSA GMBH (DE) | 2018-02-13 | — | — | US | disclosed |
| US-20160264513-A1 | Catalytic Hydrogenation for the Preparation of Amines from Amide Acetals, Ketene N,O-Acetals or Ester Imides | EVONIK DEGUSSA GMBH (DE) | 2016-09-15 | — | — | US | disclosed |
| US-20160264513-A1 | Catalytic Hydrogenation for the Preparation of Amines from Amide Acetals, Ketene N,O-Acetals or Ester Imides | EVONIK DEGUSSA GMBH (DE) | 2016-09-15 | — | — | US | disclosed |
| EP-3066070-A1 | CATALYTIC HYDROGENATION FOR THE PREPARATION OF AMINES FROM AMIDE ACETALS, KETENE N,O-ACETALS OR ESTER IMIDES | Evonik Degussa GmbH (DE) | 2016-09-14 | — | — | EP | disclosed |
| WO-2015067448-A1 | CATALYTIC HYDROGENATION FOR THE PREPARATION OF AMINES FROM AMIDE ACETALS, KETENE N,O-ACETALS OR ESTER IMIDES | EVONIK INDUSTRIES AG (DE) | 2015-05-14 | — | — | WO | disclosed |
| WO-2015067448-A1 | CATALYTIC HYDROGENATION FOR THE PREPARATION OF AMINES FROM AMIDE ACETALS, KETENE N,O-ACETALS OR ESTER IMIDES | EVONIK INDUSTRIES AG (DE) | 2015-05-14 | — | — | WO | disclosed |
| EP-2868652-A1 | Catalytic hydrogenation for the preparation of amines from amide acetals, ketene-N, O-acetals or esterimides | Evonik Industries AG (DE) | 2015-05-06 | — | — | EP | disclosed |
| EP-2868652-A1 | Catalytic hydrogenation for the preparation of amines from amide acetals, ketene-N, O-acetals or esterimides | Evonik Industries AG (DE) | 2015-05-06 | — | — | EP | disclosed |
| US-20140107135-A1 | PYRIMIDINONE INHIBITORS OF LIPOPROTEIN-ASSOCIATED PHOSPHOLIPASE A2 | AUSPEX PHARMACEUTICALS, INC. (US) | 2014-04-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160264513-A1 | Catalytic Hydrogenation for the Preparation of Amines from Amide Acetals, Ketene N,O-Acetals or Ester Imides | H1-0, H1-2, H1-10 | SIGMAR1 2144/4885DRD2 1868/4885DRD4 2344/4885 |
| US-20140107135-A1 | PYRIMIDINONE INHIBITORS OF LIPOPROTEIN-ASSOCIATED PHOSPHOLIPASE A2 | PLA2G1B, PLA2G4A, PLA2G4B | SIGMAR1 3944/4885DRD2 3047/4885DRD4 3642/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.