SCHEMBL16674346

SCHEMBL16674346

c1cc(-c2ccccc2-c2ccc(-n3c4ccccc4c4ccccc43)cc2)cc(-n2c3ccccc3c3ccccc32)c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.55
KDM4E B2RXH2 1/20 0.55
ATM Q13315 1/20 0.55
KMT2A Q03164 2/20 0.39
IL1R1 P14778 1/20 0.39
HDAC4 P56524 1/20 0.38
MEN1 O00255 1/20 0.38
ALDH1A1 P00352 1/20 0.38
MAPT P10636 1/20 0.38
HTT P42858 1/20 0.38
MAPK14 Q16539 1/20 0.36
ASH1L Q9NR48 4/20 0.36
GRM5 P41594 1/20 0.35
HSD17B10 Q99714 1/20 0.35
DUSP3 P51452 1/20 0.35
HTR1A P08908 1/20 0.34
HTR7 P34969 1/20 0.34
PDE10A Q9Y233 1/20 0.34
PTPN1 P18031 2/20 0.33
EDNRB P24530 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19075915 0.93 L3MBTL1 (0.57) L3MBTL1KDM4EATMKMT2AIL1R1
SCHEMBL24678992 0.93 L3MBTL1 (0.51) L3MBTL1KDM4EATMKMT2AIL1R1
SCHEMBL21180444 0.93 L3MBTL1 (0.47) L3MBTL1KDM4EATMKMT2AIL1R1
SCHEMBL24295147 0.92 L3MBTL1 (0.57) L3MBTL1KDM4EATMKMT2AIL1R1
SCHEMBL64366 0.91 L3MBTL1 (0.55) L3MBTL1KDM4EATMKMT2AIL1R1
SCHEMBL12853965 0.91 L3MBTL1 (0.55) L3MBTL1KDM4EATMKMT2AIL1R1
SCHEMBL24678789 0.91 L3MBTL1 (0.50) L3MBTL1KDM4EATMKMT2AIL1R1
SCHEMBL23370369 0.91 L3MBTL1 (0.53) L3MBTL1KDM4EATMKMT2AIL1R1
SCHEMBL14410401 0.91 L3MBTL1 (0.53) L3MBTL1KDM4EATMKMT2AIL1R1
SCHEMBL23370478 0.91 L3MBTL1 (0.53) L3MBTL1KDM4EATMKMT2AIL1R1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10340460-B2 Organic electroluminescent element NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2019-07-02 US disclosed
US-20150115240-A1 ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2015-04-30 US disclosed
US-20150115240-A1 ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2015-04-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10340460-B2 Organic electroluminescent element EML4, LAGE3, ELOC L3MBTL1 278/4885KDM4E 746/4885ATM 3518/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.