SCHEMBL16675204

SCHEMBL16675204

O=C(Oc1ccccc1)Oc1ccc(Nc2cc(NC(=O)c3ccc(OC(=O)Oc4ccccc4)cc3)nc(NC(=O)c3ccc(OC(=O)c4ccccc4)cc3)n2)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 7/20 0.54
MEN1 O00255 6/20 0.54
EGFR P00533 2/20 0.50
ERBB3 P21860 2/20 0.50
MAPT P10636 6/20 0.46
KDM4E B2RXH2 2/20 0.46
MAPK1 P28482 1/20 0.46
POLB P06746 1/20 0.43
ALPG P10696 1/20 0.43
ALDH1A1 P00352 2/20 0.42
HPGD P15428 2/20 0.42
PGR P06401 1/20 0.42
CYP3A4 P08684 1/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
ADORA3 P0DMS8 1/20 0.41
SCD O00767 1/20 0.41
ADORA1 P30542 1/20 0.41
GRM5 P41594 1/20 0.41
PARP10 Q53GL7 1/20 0.40
TDP1 Q9NUW8 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16675192 0.88 ADORA3 (0.50) KMT2AMEN1EGFRERBB3MAPT
SCHEMBL16677960 0.83 KMT2A (0.51) KMT2AMEN1EGFRERBB3MAPT
SCHEMBL16675207 0.81 RAB9A (0.55) KMT2AMEN1EGFRERBB3MAPT
SCHEMBL16677958 0.80 SLC2A1 (0.51) KMT2AMEN1EGFRERBB3MAPT
SCHEMBL16675182 0.79 KMT2A (0.63) KMT2AMEN1EGFRERBB3MAPT
SCHEMBL16675205 0.78 KMT2A (0.63) KMT2AMEN1EGFRERBB3MAPT
SCHEMBL16675203 0.78 GRM5 (0.63) KMT2AMEN1MAPTKDM4EPGR
SCHEMBL16675209 0.77 EGFR (0.56) KMT2AMEN1EGFRERBB3MAPT
SCHEMBL16675196 0.76 MEN1 (0.56) KMT2AMEN1MAPTKDM4EALDH1A1
SCHEMBL2623124 0.73 EGFR (0.60) KMT2AMEN1EGFRERBB3MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150114257-A1 METHOD OF PREPARING RETARDATION FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY Konica Minolta, Inc. (JP) 2015-04-30 US disclosed
US-20150114257-A1 METHOD OF PREPARING RETARDATION FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY Konica Minolta, Inc. (JP) 2015-04-30 US disclosed