SCHEMBL16675203

SCHEMBL16675203

O=C(Nc1cc(NC(=O)c2ccc(Oc3ccccc3)cc2)nc(NC(=O)c2ccc(Oc3ccccc3)cc2)n1)c1ccc(Oc2ccccc2)cc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRM5 P41594 1/20 0.63
NPC1 O15118 4/20 0.58
RAB9A P51151 4/20 0.58
MEN1 O00255 3/20 0.58
KMT2A Q03164 3/20 0.58
CASP3 P42574 1/20 0.58
SENP8 Q96LD8 1/20 0.58
SENP7 Q9BQF6 1/20 0.58
SENP6 Q9GZR1 1/20 0.58
PGR P06401 2/20 0.56
NR1H4 Q96RI1 2/20 0.55
RECQL P46063 2/20 0.53
TP53 P04637 1/20 0.53
ATM Q13315 1/20 0.52
ADORA3 P0DMS8 2/20 0.52
KCNQ3 O43525 1/20 0.51
KCNQ2 O43526 1/20 0.51
KCNE1 P15382 1/20 0.51
KCNQ1 P51787 1/20 0.51
KDM4E B2RXH2 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16675192 0.89 ADORA3 (0.50) GRM5NPC1RAB9AMEN1KMT2A
SCHEMBL16675189 0.82 KMT2A (0.73) NPC1RAB9AMEN1KMT2ARECQL
SCHEMBL16675194 0.79 RAB9A (0.63) NPC1RAB9AMEN1KMT2ARECQL
SCHEMBL821939 0.79 ADORA1 (0.56) GRM5NPC1RAB9AMEN1KMT2A
SCHEMBL15305767 0.79 NPC1 (0.69) NPC1RAB9AMEN1KMT2ACASP3
SCHEMBL15308171 0.79 NPC1 (0.69) NPC1RAB9AMEN1KMT2ACASP3
SCHEMBL16675196 0.78 MEN1 (0.56) NPC1RAB9AMEN1KMT2ARECQL
SCHEMBL28656164 0.78 RAB9A (0.76) GRM5NPC1RAB9AMEN1KMT2A
SCHEMBL16675204 0.78 KMT2A (0.54) GRM5NPC1RAB9AMEN1KMT2A
SCHEMBL15308163 0.77 MEN1 (0.66) NPC1RAB9AMEN1KMT2ARECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150114257-A1 METHOD OF PREPARING RETARDATION FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY Konica Minolta, Inc. (JP) 2015-04-30 US disclosed
US-20150114257-A1 METHOD OF PREPARING RETARDATION FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY Konica Minolta, Inc. (JP) 2015-04-30 US disclosed