Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 5/20 | 0.68 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.60 |
| ▸ | HTR1A | P08908 | 8/20 | 0.54 |
| ▸ | HTR1D | P28221 | 6/20 | 0.54 |
| ▸ | HTR1B | P28222 | 6/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.49 |
| ▸ | MPO | P05164 | 3/20 | 0.49 |
| ▸ | HTR2A | P28223 | 6/20 | 0.49 |
| ▸ | HTR2B | P41595 | 2/20 | 0.49 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.49 |
| ▸ | HTR3B | O95264 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | DRD1 | P21728 | 1/20 | 0.49 |
| ▸ | HTR1E | P28566 | 1/20 | 0.49 |
| ▸ | HTR1F | P30939 | 1/20 | 0.49 |
| ▸ | HTR7 | P34969 | 1/20 | 0.49 |
| ▸ | DRD3 | P35462 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10681114 | 0.87 | HTR1A (0.72) | HTR2CCYP2D6HTR1AHTR1DHTR1B | |
| SCHEMBL16791392 | 0.83 | HPGD (0.68) | HTR2CCYP2D6HTR1AHTR1DHTR1B | |
| SCHEMBL1750326 | 0.83 | HTR1A (0.76) | HTR2CCYP2D6HTR1AHTR1DHTR1B | |
| SCHEMBL20424804 | 0.83 | HTR2C (0.59) | HTR2CCYP2D6HTR1AHTR1DHTR1B | |
| SCHEMBL9697763 | 0.83 | HTR1A (0.49) | HTR2CCYP2D6HTR1AHTR1DHTR1B | |
| SCHEMBL12352649 | 0.83 | KDM4E (0.69) | HTR2CCYP2D6HTR1AHTR1DHTR1B | |
| SCHEMBL233744 | 0.81 | HTR2C (1.00) | HTR2CCYP2D6HTR1AHTR1DHTR1B | |
| SCHEMBL29351067 | 0.81 | HTR2C (1.00) | HTR2CCYP2D6HTR1AHTR1DHTR1B | |
| SCHEMBL8097802 | 0.81 | HTR2C (0.56) | HTR2CCYP2D6HTR1AHTR1DHTR1B | |
| SCHEMBL7481572 | 0.79 | HTR2C (0.55) | HTR2CCYP2D6HTR1AHTR1DHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11737462-B2 | Methods for modulating plant response to environmentally-induced stress | HOWARD UNIVERSITY (US) | 2023-08-29 | — | — | US | disclosed |
| US-20150119250-A1 | METHODS FOR MODULATING PLANT RESPONSE TO ENVIRONMENTALLY-INDUCED STRESS | GEORGETOWN UNIVERSITY | 2015-04-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11737462-B2 | Methods for modulating plant response to environmentally-induced stress | RACK1, ROS1, HSF1 | HTR2C 4128/4885CYP2D6 4707/4885HTR1A 3190/4885 |
| US-20150119250-A1 | METHODS FOR MODULATING PLANT RESPONSE TO ENVIRONMENTALLY-INDUCED STRESS | RACK1, ROS1, HSF1 | HTR2C 4128/4885CYP2D6 4707/4885HTR1A 3190/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.