Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 6/20 | 0.49 |
| ▸ | HTR1D | P28221 | 5/20 | 0.49 |
| ▸ | HTR1B | P28222 | 5/20 | 0.49 |
| ▸ | HTR2C | P28335 | 2/20 | 0.48 |
| ▸ | MPO | P05164 | 8/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | HTR2A | P28223 | 2/20 | 0.43 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.43 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.43 |
| ▸ | HTR3B | O95264 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | DRD1 | P21728 | 1/20 | 0.43 |
| ▸ | HTR1E | P28566 | 1/20 | 0.43 |
| ▸ | HTR1F | P30939 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16675461 | 0.83 | HTR2C (0.68) | HTR1AHTR1DHTR1BHTR2CMPO | |
| SCHEMBL8807628 | 0.82 | HTR2C (0.67) | HTR1AHTR1DHTR1BHTR2CSLC6A4 | |
| SCHEMBL28486981 | 0.82 | MPO (0.51) | HTR1AHTR1DHTR1BMPOSLC6A4 | |
| SCHEMBL10681114 | 0.80 | HTR1A (0.72) | HTR1AHTR1DHTR1BHTR2CMPO | |
| SCHEMBL8808469 | 0.80 | SLC6A4 (0.67) | HTR1AHTR1DHTR1BHTR2CMPO | |
| SCHEMBL8544422 | 0.79 | HPGD (0.58) | HTR1AHTR1DHTR1BHTR2CMPO | |
| SCHEMBL4637101 | 0.79 | MPO (0.73) | HTR1AMPOSLC6A4HTR2ATRPM8 | |
| SCHEMBL9257648 | 0.77 | HTR7 (0.68) | HTR1AHTR1DHTR1BHTR2CMPO | |
| SCHEMBL12352649 | 0.77 | KDM4E (0.69) | HTR1AHTR1DHTR1BHTR2CMPO | |
| SCHEMBL16791392 | 0.77 | HPGD (0.68) | HTR1AHTR1DHTR1BHTR2CMPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0496222-A1 | Indole derivatives | MERCK PATENT GmbH (DE) | 1992-07-29 | — | — | EP | disclosed |