Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | CASP6 | P55212 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.40 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.40 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | KDM4A | O75164 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8627702 | 0.80 | ALDH1A1 (0.46) | LMNASMN1; SMN2RAB9AALDH1A1NPC1 | |
| SCHEMBL5924397 | 0.72 | KMT2A (0.75) | LMNARAB9AALDH1A1KMT2AGAA | |
| SCHEMBL8629665 | 0.69 | NR1I2 (0.39) | LMNASMN1; SMN2RAB9AALDH1A1NPC1 | |
| SCHEMBL8628370 | 0.69 | HSD11B1 (0.46) | LMNASMN1; SMN2RAB9AALDH1A1KMT2A | |
| SCHEMBL21673521 | 0.68 | PBRM1 (0.66) | SMN1; SMN2RAB9AMAPTBRD4NR1I2 | |
| SCHEMBL28898204 | 0.65 | ALDH1A1 (0.48) | LMNASMN1; SMN2RAB9AALDH1A1NPC1 | |
| SCHEMBL13916731 | 0.64 | AVPR1A (0.53) | LMNASMN1; SMN2ALDH1A1KMT2AHSD17B10 | |
| SCHEMBL10940862 | 0.64 | ALDH1A1 (1.00) | LMNASMN1; SMN2RAB9AALDH1A1NPC1 | |
| SCHEMBL28574 | 0.64 | ALDH1A1 (0.67) | LMNASMN1; SMN2RAB9AALDH1A1NPC1 | |
| SCHEMBL30442890 | 0.64 | ALDH1A1 (0.67) | LMNASMN1; SMN2RAB9AALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150119250-A1 | METHODS FOR MODULATING PLANT RESPONSE TO ENVIRONMENTALLY-INDUCED STRESS | GEORGETOWN UNIVERSITY | 2015-04-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150119250-A1 | METHODS FOR MODULATING PLANT RESPONSE TO ENVIRONMENTALLY-INDUCED STRESS | RACK1, ROS1, HSF1 | LMNA 3460/4885SMN1; SMN2 4793/4885RAB9A 176/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.