Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 2/20 | 0.39 |
| ▸ | SMARCA2 | P51531 | 2/20 | 0.39 |
| ▸ | SMARCA4 | P51532 | 2/20 | 0.39 |
| ▸ | PBRM1 | Q86U86 | 2/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | KDM4A | O75164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | LMNA | P02545 | 5/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16675470 | 0.69 | LMNA (0.47) | NR1I2SMARCA2SMARCA4PBRM1BRD4 | |
| SCHEMBL8627702 | 0.68 | ALDH1A1 (0.46) | NR1I2SMARCA2SMARCA4PBRM1BRD4 | |
| SCHEMBL28937585 | 0.66 | ALDH1A1 (0.63) | SMN1; SMN2HSD17B10ALDH1A1LMNAHPGD | |
| SCHEMBL7845497 | 0.66 | ALDH1A1 (0.63) | SMN1; SMN2HSD17B10ALDH1A1LMNAHPGD | |
| SCHEMBL27399790 | 0.64 | ALDH1A1 (0.44) | KDM4ASMN1; SMN2HSD17B10ALDH1A1LMNA | |
| SCHEMBL8630057 | 0.64 | BCHE (0.41) | SMN1; SMN2HSD17B10ALDH1A1LMNAHPGD | |
| Hydroxyamine SCHEMBL28237907 | 0.63 | ALDH1A1 (0.60) | NR1I2SMARCA2SMARCA4PBRM1BRD4 | |
| SCHEMBL27651172 | 0.63 | IDO1 (0.42) | NR1I2SMARCA2SMARCA4PBRM1BRD4 | |
| SCHEMBL29623192 | 0.63 | ALDH1A1 (0.67) | SMN1; SMN2HSD17B10ALDH1A1LMNAHPGD | |
| SCHEMBL30442890 | 0.63 | ALDH1A1 (0.67) | SMN1; SMN2HSD17B10ALDH1A1LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE35754-E | FOR TREATING BACTERIAL INFECTIONS | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-03-24 | — | — | US | disclosed |
| US-5710146-A | ANTIBIOTICS FOR BACTERICIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-01-20 | — | — | US | disclosed |
| US-5089490-A | Cephem derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-02-18 | — | — | US | disclosed |
| US-4758556-A | Cephem derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-07-19 | — | — | US | disclosed |
| US-4399131-A | Cephem derivatives | HOECHST AG (DE) | 1983-08-16 | — | — | US | disclosed |
| US-4278793-A | ANTIBIOTICS, BACTERICIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-07-14 | — | — | US | disclosed |