Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.69 |
| ▸ | NPC1 | O15118 | 3/20 | 0.60 |
| ▸ | RAB9A | P51151 | 3/20 | 0.60 |
| ▸ | LMNA | P02545 | 5/20 | 0.58 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | ALPG | P10696 | 3/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16681840 | 0.95 | LMNA (0.63) | SMN1; SMN2ALDH1A1NPC1RAB9ALMNA | |
| SCHEMBL16675474 | 0.81 | LMNA (0.57) | SMN1; SMN2ALDH1A1NPC1RAB9ALMNA | |
| SCHEMBL16681839 | 0.79 | MEN1 (0.56) | SMN1; SMN2ALDH1A1NPC1RAB9ALMNA | |
| SCHEMBL27173136 | 0.79 | TUBB4A (0.73) | SMN1; SMN2ALDH1A1NPC1RAB9ALMNA | |
| SCHEMBL25337471 | 0.75 | ALDH1A1 (0.64) | SMN1; SMN2ALDH1A1NPC1RAB9ALMNA | |
| SCHEMBL4201147 | 0.75 | POLB (0.76) | ALDH1A1LMNAPOLBMAPTHPGD | |
| SCHEMBL23527313 | 0.74 | ALDH1A1 (0.84) | ALDH1A1NPC1RAB9ALMNAPOLB | |
| SCHEMBL4209017 | 0.74 | POLB (0.80) | ALDH1A1NPC1RAB9ALMNAPOLB | |
| SCHEMBL26047877 | 0.72 | HPGD (0.50) | SMN1; SMN2ALDH1A1NPC1RAB9ALMNA | |
| SCHEMBL6192068 | 0.72 | MAPT (0.91) | SMN1; SMN2ALDH1A1LMNARXFP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150119250-A1 | METHODS FOR MODULATING PLANT RESPONSE TO ENVIRONMENTALLY-INDUCED STRESS | GEORGETOWN UNIVERSITY | 2015-04-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150119250-A1 | METHODS FOR MODULATING PLANT RESPONSE TO ENVIRONMENTALLY-INDUCED STRESS | RACK1, ROS1, HSF1 | SMN1; SMN2 4793/4885ALDH1A1 2652/4885NPC1 4575/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.