Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 2/20 | 0.73 |
| ▸ | TUBB | P07437 | 2/20 | 0.73 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.73 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.73 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.73 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.73 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.73 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.73 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.73 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.73 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.73 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.73 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.73 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.73 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.62 |
| ▸ | TSHR | P16473 | 3/20 | 0.60 |
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16675473 | 0.79 | SMN1; SMN2 (0.69) | ALDH1A1SMN1; SMN2MAPTPOLBHPGD | |
| SCHEMBL4211692 | 0.77 | KMT2A (0.66) | ALDH1A1SMN1; SMN2TSHRMAPTCYP1A2 | |
| SCHEMBL16675484 | 0.74 | TUBB4A (0.80) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL16681840 | 0.73 | LMNA (0.63) | ALDH1A1SMN1; SMN2TSHRMAPTPOLB | |
| SCHEMBL29642719 | 0.73 | ALDH1A1 (0.72) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL4348643 | 0.72 | MAPT (0.55) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL4348305 | 0.71 | TP53 (0.58) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL14606122 | 0.70 | LMNA (0.84) | ALDH1A1SMN1; SMN2TSHRMAPTPOLB | |
| SCHEMBL16675455 | 0.70 | L3MBTL1 (0.66) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL4344836 | 0.70 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2TSHRMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3959200-B1 | NEW TRIAZOLE AND TRIAZOLOTHIADIAZINE DERIVATIVES EXERTING CYTOTOXIC AND APOPTOTIC EFFECTS ON A549 CELLS THROUGH AKT INHIBITION | ANADOLU UNIV (TR) | 2024-03-20 | — | — | EP | disclosed |
| EP-3959200-A1 | NEW TRIAZOLE AND TRIAZOLOTHIADIAZINE DERIVATIVES EXERTING CYTOTOXIC AND APOPTOTIC EFFECTS ON A549 CELLS THROUGH AKT INHIBITION | Anadolu Universitesi (TR) | 2022-03-02 | — | — | EP | disclosed |