Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 6/20 | 0.62 |
| ▸ | JAK2 | O60674 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | GLA | P06280 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | IDO1 | P14902 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | TDO2 | P48775 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.53 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.53 |
| ▸ | TNKS | O95271 | 4/20 | 0.53 |
| ▸ | TNKS2 | Q9H2K2 | 4/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16667971 | 0.91 | PTGES (0.62) | PTGESJAK2GAAKDM4EMEN1 | |
| SCHEMBL16675555 | 0.91 | PTGES (0.62) | PTGESJAK2GAAKDM4EMEN1 | |
| SCHEMBL30373338 | 0.91 | PTGES (0.62) | PTGESJAK2GAAKDM4EMEN1 | |
| SCHEMBL29829906 | 0.86 | ALDH1A1 (0.60) | PTGESJAK2GAAKDM4EMEN1 | |
| SCHEMBL2951161 | 0.86 | ALDH1A1 (0.60) | PTGESJAK2GAAKDM4EMEN1 | |
| SCHEMBL30338162 | 0.84 | TNKS (0.48) | PTGESJAK2GAAIDO1TDO2 | |
| SCHEMBL13007531 | 0.83 | PTGES (0.54) | PTGESJAK2GAAKDM4EMEN1 | |
| SCHEMBL14023475 | 0.83 | MEN1 (0.57) | PTGESJAK2GAAKDM4EMEN1 | |
| SCHEMBL762462 | 0.83 | PTGES (0.54) | PTGESJAK2GAAKDM4EMEN1 | |
| SCHEMBL29861634 | 0.83 | PTGES (0.55) | PTGESJAK2GAAKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105254570-A | Method for preparing 2-aryl-1H-phenanthro (9,10-d) imidazole derivative in catalyzed mode | UNIV ANHUI TECHNOLOGY | 2016-01-20 | — | — | CN | disclosed |