Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | GAA | P10253 | 3/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | GLA | P06280 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | PTGES | O14684 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | IDO1 | P14902 | 1/20 | 0.60 |
| ▸ | RECQL | P46063 | 1/20 | 0.60 |
| ▸ | TDO2 | P48775 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | ATM | Q13315 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2951161 | 1.00 | ALDH1A1 (0.60) | ALDH1A1GAAKDM4EMEN1GLA | |
| SCHEMBL30373338 | 0.94 | PTGES (0.62) | ALDH1A1GAAKDM4EMEN1GLA | |
| SCHEMBL16667971 | 0.94 | PTGES (0.62) | ALDH1A1GAAKDM4EMEN1GLA | |
| SCHEMBL16675555 | 0.94 | PTGES (0.62) | ALDH1A1GAAKDM4EMEN1GLA | |
| SCHEMBL29861634 | 0.86 | PTGES (0.55) | ALDH1A1GAAKDM4EMEN1GLA | |
| SCHEMBL13007531 | 0.86 | PTGES (0.54) | ALDH1A1GAAKDM4EMEN1GLA | |
| SCHEMBL762462 | 0.86 | PTGES (0.54) | ALDH1A1GAAKDM4EMEN1GLA | |
| SCHEMBL29065756 | 0.86 | GAA (0.62) | ALDH1A1GAAKDM4EMEN1GLA | |
| SCHEMBL14023475 | 0.86 | MEN1 (0.57) | ALDH1A1GAAKDM4EMEN1GLA | |
| SCHEMBL28049482 | 0.86 | PTGES (0.62) | ALDH1A1GAAKDM4EMEN1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115029731-A | Heteroatom-doped covalent organic framework material and preparation method and application thereof | 齐齐哈尔大学 | 2022-09-09 | — | — | CN | disclosed |