SCHEMBL16675655

SCHEMBL16675655

CC(C)C1CC(=O)N(c2ccc(Cc3ccc(N4C(=O)CC(C(C)C)C4=O)cc3)cc2)C1=O

nearest known ligand 0.52

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.48
FAAH O00519 1/20 0.43
MGLL Q99685 1/20 0.43
L3MBTL1 Q9Y468 2/20 0.43
LMNA P02545 2/20 0.42
ALDH1A1 P00352 6/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
KCNH2 Q12809 1/20 0.41
POLB P06746 3/20 0.41
HPGD P15428 3/20 0.40
HTT P42858 2/20 0.40
HSP90AA1 P07900 1/20 0.40
TP53 P04637 1/20 0.40
MAPT P10636 1/20 0.40
MEN1 O00255 1/20 0.40
TSHR P16473 1/20 0.40
KMT2A Q03164 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
ALOX12 P18054 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16675654 0.93 MGLL (0.57) GAAFAAHMGLLL3MBTL1LMNA
SCHEMBL18700229 0.93 GAA (0.43) GAAFAAHMGLLL3MBTL1LMNA
SCHEMBL16118177 0.89 ALDH1A1 (0.50) GAAMGLLL3MBTL1LMNAALDH1A1
SCHEMBL14750419 0.87 MGLL (0.50) GAAFAAHMGLLL3MBTL1LMNA
SCHEMBL16118178 0.84 GAA (0.49) GAAL3MBTL1LMNAALDH1A1POLB
SCHEMBL22632065 0.84 ALDH1A1 (0.56) GAALMNAALDH1A1POLBHPGD
SCHEMBL16449760 0.83 HSP90AA1 (0.55) GAAFAAHMGLLL3MBTL1LMNA
SCHEMBL12252718 0.82 GAA (0.58) GAALMNAALDH1A1SMN1; SMN2MAPT
SCHEMBL19454622 0.81 GAA (0.48) GAAL3MBTL1LMNAALDH1A1POLB
SCHEMBL20382862 0.80 GAA (0.44) GAAL3MBTL1LMNAALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9611359-B2 Maleimide-terminated sulfur-containing polymers, compositions thereof, and uses thereof PRC-DESOTO INTERNATIONAL, INC. (US) 2017-04-04 US disclosed
US-20150119549-A1 MALEIMIDE-TERMINATED SULFUR-CONTAINING POLYMERS, COMPOSITIONS THEREOF, AND USES THEREOF PRC-DESOTO INTERNATIONAL, INC. (US) 2015-04-30 US disclosed