Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.41 |
| ▸ | MAPT | P10636 | 7/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16675655 | 0.93 | GAA (0.48) | GAAL3MBTL1ALDH1A1MAPTLMNA | |
| SCHEMBL16681934 | 0.89 | ALDH1A1 (0.47) | GAAL3MBTL1ALDH1A1MAPTTDP1 | |
| SCHEMBL16675654 | 0.86 | MGLL (0.57) | GAAL3MBTL1ALDH1A1TDP1LMNA | |
| SCHEMBL16118177 | 0.83 | ALDH1A1 (0.50) | GAAL3MBTL1ALDH1A1MAPTTDP1 | |
| SCHEMBL14159540 | 0.82 | MGLL (0.62) | GAAALDH1A1MAPTTDP1MAPK1 | |
| SCHEMBL14750419 | 0.81 | MGLL (0.50) | GAAL3MBTL1ALDH1A1MAPTLMNA | |
| SCHEMBL18466208 | 0.79 | ALDH1A1 (0.50) | GAAL3MBTL1ALDH1A1MAPTTDP1 | |
| SCHEMBL16566170 | 0.79 | ALDH1A1 (0.50) | GAAL3MBTL1ALDH1A1MAPTTDP1 | |
| SCHEMBL16118178 | 0.78 | GAA (0.49) | GAAL3MBTL1ALDH1A1LMNARAB9A | |
| SCHEMBL15370241 | 0.78 | LMNA (0.43) | ALDH1A1MAPTTDP1LMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9611359-B2 | Maleimide-terminated sulfur-containing polymers, compositions thereof, and uses thereof | PRC-DESOTO INTERNATIONAL, INC. (US) | 2017-04-04 | — | — | US | disclosed |