Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 10/20 | 0.46 |
| ▸ | SETD2 | Q9BYW2 | 2/20 | 0.43 |
| ▸ | NSD2 | O96028 | 1/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 2/20 | 0.41 |
| ▸ | HTR6 | P50406 | 2/20 | 0.41 |
| ▸ | SOS1 | Q07889 | 2/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12027636 | 1.00 | MCHR1 (0.46) | MCHR1SETD2NSD2JAK2BRD4 | |
| SCHEMBL27959338 | 1.00 | MCHR1 (0.46) | MCHR1SETD2NSD2JAK2BRD4 | |
| SCHEMBL1749702 | 0.82 | MCHR1 (0.55) | MCHR1 | |
| SCHEMBL16675746 | 0.81 | PDK2 (0.42) | — | |
| SCHEMBL16675693 | 0.81 | ADRA2C (0.50) | MCHR1HTR2BHTR6KCNH2 | |
| SCHEMBL14980549 | 0.81 | NOTUM (0.57) | MCHR1HTR2BHTR6SOS1KCNH2 | |
| SCHEMBL12027635 | 0.81 | ADRA2C (0.50) | MCHR1HTR2BHTR6KCNH2 | |
| SCHEMBL19476382 | 0.80 | JAK2 (0.49) | JAK2BRD4 | |
| SCHEMBL4186891 | 0.79 | NPY5R (0.48) | MCHR1HTR2BHTR6SOS1KCNH2 | |
| SCHEMBL16719407 | 0.78 | MCHR1 (0.56) | MCHR1HTR6KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2188251-B1 | ARYLSULFONAMIDES WITH ANALGESIC ACTIVITY | BOEHRINGER INGELHEIM INT (DE) | 2015-04-29 | — | — | EP | disclosed |