Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | BPTF | Q12830 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.36 |
| ▸ | JAK3 | P52333 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | GHSR | Q92847 | 3/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27308406 | 0.90 | LMNA (0.45) | LMNAALDH1A1MAPTL3MBTL1MEN1 | |
| SCHEMBL16675702 | 0.81 | MCHR1 (0.46) | — | |
| SCHEMBL12027636 | 0.81 | MCHR1 (0.46) | — | |
| SCHEMBL27959338 | 0.81 | MCHR1 (0.46) | — | |
| SCHEMBL23657315 | 0.79 | IDH2 (0.40) | NOTUMALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL15928755 | 0.79 | ADRA2C (0.54) | PDK2NOTUMLMNABPTFALDH1A1 | |
| SCHEMBL16675695 | 0.79 | ADRA2C (0.54) | PDK2NOTUMLMNABPTFALDH1A1 | |
| SCHEMBL10472128 | 0.78 | NOTUM (0.61) | NOTUMLMNAALDH1A1MAPTL3MBTL1 | |
| SCHEMBL12862539 | 0.78 | OPRM1 (0.50) | PDK2NOTUMALDH1A1MEN1KMT2A | |
| SCHEMBL18801748 | 0.76 | PRMT6 (0.56) | ALDH1A1MAPTMEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2188251-B1 | ARYLSULFONAMIDES WITH ANALGESIC ACTIVITY | BOEHRINGER INGELHEIM INT (DE) | 2015-04-29 | — | — | EP | disclosed |