Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 1/20 | 0.48 |
| ▸ | HTR6 | P50406 | 4/20 | 0.43 |
| ▸ | HTR2B | P41595 | 2/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 5/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | HTR1D | P28221 | 2/20 | 0.39 |
| ▸ | HTR3A | P46098 | 2/20 | 0.39 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.39 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.39 |
| ▸ | BTK | Q06187 | 2/20 | 0.39 |
| ▸ | MRGPRX2 | Q96LB1 | 2/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | HTR1B | P28222 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.39 |
| ▸ | SOS1 | Q07889 | 2/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3665104 | 0.92 | NPY5R (0.43) | NPY5RHTR6HTR2BALOX5MCHR1 | |
| SCHEMBL2174889 | 0.91 | NPY5R (0.53) | NPY5RHTR2BALOX5TMEM97 | |
| SCHEMBL26881412 | 0.84 | NPY5R (0.56) | NPY5RHTR6HTR2BALOX5 | |
| SCHEMBL26881395 | 0.84 | NPY5R (0.56) | NPY5RHTR6HTR2BALOX5 | |
| SCHEMBL25966616 | 0.84 | NPY5R (0.53) | NPY5RALOX5MCHR1NOTUM | |
| SCHEMBL14905667 | 0.84 | NPY5R (0.53) | NPY5RALOX5MCHR1NOTUM | |
| SCHEMBL25966239 | 0.84 | NPY5R (0.53) | NPY5RALOX5MCHR1NOTUM | |
| SCHEMBL14980549 | 0.83 | NOTUM (0.57) | NPY5RHTR6HTR2BMCHR1KCNH2 | |
| SCHEMBL12027635 | 0.83 | ADRA2C (0.50) | HTR6HTR2BMCHR1KCNH2NOTUM | |
| SCHEMBL16675693 | 0.83 | ADRA2C (0.50) | HTR6HTR2BMCHR1KCNH2NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119684317-A | Macrocyclic compound and application thereof | 郑州德迈药业有限公司 | 2025-03-25 | — | — | CN | disclosed |
| EP-2242742-B1 | PYRIDINE DERIVATIVES | NOVARTIS AG (CH) | 2015-12-02 | — | — | EP | disclosed |
| US-8343966-B2 | Organic compounds | NOVARTIS AG (CH) | 2013-01-01 | — | — | US | disclosed |
| US-20090215776-A1 | Organic compounds | ADCOCK CLAIRE | 2009-08-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090215776-A1 | Organic compounds | REN, RXFP1, MYLK | NPY5R 1838/4885HTR6 4038/4885HTR2B 3880/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.