Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2R | P25116 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | JAK2 | O60674 | 1/20 | 0.46 |
| ▸ | JAK1 | P23458 | 1/20 | 0.46 |
| ▸ | TYK2 | P29597 | 1/20 | 0.46 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 6/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19255780 | 0.78 | F2R (0.60) | F2RGAATRPA1RAB9AMAPT | |
| SCHEMBL16670340 | 0.77 | ITGB1 (0.43) | GAATRPA1HTTJAK2JAK1 | |
| SCHEMBL8677157 | 0.77 | VNN1 (0.50) | RAB9AMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL30739749 | 0.77 | JAK2 (0.71) | GAAHTTJAK2JAK1TYK2 | |
| SCHEMBL18642994 | 0.75 | F2R (0.49) | F2RGAATYK2CYP1A2MEN1 | |
| SCHEMBL14402655 | 0.74 | RIPK1 (0.46) | F2RMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL18642732 | 0.74 | TYK2 (0.48) | F2RGAAJAK2JAK1TYK2 | |
| SCHEMBL16583943 | 0.73 | GAA (0.59) | F2RGAATRPA1HTTJAK2 | |
| SCHEMBL28326824 | 0.71 | KMT2A (0.73) | GAAHTTJAK2JAK1TYK2 | |
| SCHEMBL19576334 | 0.71 | GAA (0.56) | GAAHTTJAK2JAK1TYK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015061204-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | INFINITY PHARMACEUTICALS, INC. (US) | 2015-04-30 | — | — | WO | disclosed |