Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2R | P25116 | 9/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16854242 | 0.85 | PLK1 (0.55) | F2RALDH1A1MAPTHPGDMAPK1 | |
| SCHEMBL19576142 | 0.84 | GAA (0.50) | SMN1; SMN2NPC1RAB9AGAA | |
| SCHEMBL19576334 | 0.80 | GAA (0.56) | MAPTSMN1; SMN2NPC1RAB9AGAA | |
| SCHEMBL5261314 | 0.80 | SMN1; SMN2 (0.68) | ALDH1A1MAPTMAPK1SMN1; SMN2CYP2C19 | |
| SCHEMBL19935743 | 0.80 | KMT2A (0.49) | ALDH1A1SMN1; SMN2RAB9AGAATRPA1 | |
| SCHEMBL19576325 | 0.80 | KMT2A (0.49) | ALDH1A1SMN1; SMN2RAB9AGAATRPA1 | |
| SCHEMBL16584740 | 0.79 | F10 (0.43) | F2RALDH1A1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL19209038 | 0.79 | GAA (0.44) | ALDH1A1MAPTNPC1RAB9AGAA | |
| SCHEMBL19209037 | 0.79 | GAA (0.44) | ALDH1A1MAPTNPC1RAB9AGAA | |
| SCHEMBL16677246 | 0.78 | F2R (0.49) | F2RALDH1A1MAPTHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017134607-A1 | A PROCESS FOR THE PREPARATION OF PHOSPHATIDYLINOSITOL 3-KINASE INHIBITOR | LUPIN LIMITED (IN) | 2017-08-10 | — | — | WO | disclosed |