Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.46 |
| ▸ | FBP1 | P09467 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alcohol SCHEMBL11148831 | 0.95 | FBP1 (0.46) | TDP1SMN1; SMN2PDE7AFBP1TSHR | |
| SCHEMBL8361517 | 0.86 | TDP1 (0.58) | TDP1SMN1; SMN2FBP1TSHRGPR35 | |
| SCHEMBL7166893 | 0.86 | TDP1 (0.46) | TDP1SMN1; SMN2PDE7ATSHRGPR35 | |
| SCHEMBL3599344 | 0.83 | SMN1; SMN2 (0.47) | TDP1SMN1; SMN2PDE7ATSHRGPR35 | |
| SCHEMBL6741088 | 0.83 | SMN1; SMN2 (0.47) | TDP1SMN1; SMN2PDE7ATSHRGPR35 | |
| SCHEMBL6036699 | 0.83 | ALDH1A1 (0.47) | TDP1TSHRGPR35MAPTALDH1A1 | |
| SCHEMBL4048581 | 0.83 | TDP1 (0.47) | TDP1SMN1; SMN2PDE7ATSHRGPR35 | |
| SCHEMBL4938054 | 0.82 | TDP1 (0.46) | TDP1SMN1; SMN2PDE7ATSHRGPR35 | |
| SCHEMBL3597823 | 0.82 | TDP1 (0.42) | TDP1SMN1; SMN2PDE7ATSHRGPR35 | |
| SCHEMBL1374438 | 0.81 | GPR35 (0.48) | TDP1SMN1; SMN2PDE7ATSHRGPR35 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2486115-A1 | ELECTRORHEOLOGICAL FLUID COMPRISING ORGANIC DOPANTS, AND USE THEREOF | Fraunhofer Gesellschaft zur Förderung der angewandten Wissenschaft E.V. (DE) | 2012-08-15 | — | — | EP | disclosed |
| WO-2011042117-A1 | ELECTRORHEOLOGICAL FLUID COMPRISING ORGANIC DOPANTS, AND USE THEREOF | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) | 2011-04-14 | — | — | WO | disclosed |
| US-20100016285-A1 | HETEROCYCLIDENE-N-(ARYL) ACETAMIDE DERIVATIVE | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2010-01-21 | — | — | US | disclosed |
| EP-0319817-A2 | Phenylamino- and phenylaminomethyl pyridines, and hair-dyeing products containing them | Henkel Kommanditgesellschaft auf Aktien (DE) | 1989-06-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100016285-A1 | HETEROCYCLIDENE-N-(ARYL) ACETAMIDE DERIVATIVE | CCNY, CCND3, NSD3 | TDP1 4591/4885SMN1; SMN2 1047/4885PDE7A 4844/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.