Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP14 | P54578 | 1/20 | 0.33 |
| ▸ | FEN1 | P39748 | 1/20 | 0.32 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | REN | P00797 | 1/20 | 0.30 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.30 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1667884 | 0.85 | USP14 (0.33) | USP14FEN1ALDH1A1RENPDE4B | |
| SCHEMBL1668166 | 0.82 | USP14 (0.33) | USP14FEN1GRM1REN | |
| SCHEMBL1668164 | 0.82 | USP14 (0.33) | USP14FEN1GRM1REN | |
| SCHEMBL1667747 | 0.79 | USP14 (0.33) | USP14ALDH1A1REN | |
| SCHEMBL1670567 | 0.78 | GAA (0.30) | — | |
| SCHEMBL1667702 | 0.77 | BRD4 (0.36) | USP14ALDH1A1 | |
| SCHEMBL1667778 | 0.77 | USP14 (0.36) | USP14FEN1ALDH1A1RENPDE4B | |
| SCHEMBL1670139 | 0.76 | USP14 (0.32) | USP14 | |
| SCHEMBL1667678 | 0.75 | FEN1 (0.33) | USP14FEN1ALDH1A1PDE4BMAPK8 | |
| SCHEMBL1667733 | 0.74 | FEN1 (0.32) | USP14FEN1ALDH1A1MAPK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011042474-A1 | NOVEL ESTROGEN RECEPTOR LIGANDS | KARO BIO AB (SE) | 2011-04-14 | — | — | WO | claimed |