Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP14 | P54578 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | FEN1 | P39748 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | REN | P00797 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | APP | P05067 | 1/20 | 0.30 |
| ▸ | MYC | P01106 | 2/20 | 0.30 |
| ▸ | HTT | P42858 | 2/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.30 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12797301 | 0.81 | HSP90AA1 (0.41) | USP14ALDH1A1FEN1KDM4ECYP2C19 | |
| SCHEMBL1077439 | 0.81 | HDAC6 (0.36) | USP14ALDH1A1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL1667774 | 0.81 | NTRK1 (0.37) | USP14ALDH1A1FEN1KDM4EMAPT | |
| SCHEMBL1667776 | 0.81 | NTRK1 (0.37) | USP14ALDH1A1FEN1KDM4EMAPT | |
| SCHEMBL1667678 | 0.80 | FEN1 (0.33) | USP14ALDH1A1FEN1CYP2C19TSHR | |
| SCHEMBL1667733 | 0.79 | FEN1 (0.32) | USP14ALDH1A1FEN1KDM4EMAPT | |
| SCHEMBL1667884 | 0.78 | USP14 (0.33) | USP14ALDH1A1FEN1PDE4AREN | |
| SCHEMBL1668168 | 0.77 | USP14 (0.33) | USP14ALDH1A1FEN1RENPDE4B | |
| SCHEMBL1667702 | 0.76 | BRD4 (0.36) | USP14ALDH1A1KDM4EMAPTCYP2C19 | |
| SCHEMBL1667747 | 0.76 | USP14 (0.33) | USP14ALDH1A1MAPTSMN1; SMN2REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011042474-A1 | NOVEL ESTROGEN RECEPTOR LIGANDS | KARO BIO AB (SE) | 2011-04-14 | — | — | WO | disclosed |