Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 4/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | GPR35 | Q9HC97 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TTR | P02766 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7784631 | 0.90 | HTT (0.58) | HTTPOLBALDH1A1GPR35KMT2A | |
| SCHEMBL4000997 | 0.84 | HTT (0.53) | HTTPOLBALDH1A1GPR35KMT2A | |
| SCHEMBL8744302 | 0.80 | ALDH1A1 (0.53) | HTTPOLBALDH1A1GPR35KMT2A | |
| SCHEMBL1667948 | 0.79 | GPR35 (0.51) | HTTPOLBALDH1A1GPR35KMT2A | |
| SCHEMBL10619763 | 0.79 | CYP1A2 (0.58) | HTTPOLBALDH1A1GPR35KMT2A | |
| SCHEMBL5083326 | 0.77 | GPR35 (0.62) | HTTPOLBALDH1A1GPR35KMT2A | |
| SCHEMBL3475651 | 0.75 | HTT (0.49) | HTTPOLBALDH1A1GPR35KMT2A | |
| SCHEMBL13941258 | 0.75 | HTT (0.58) | HTTPOLBALDH1A1GPR35KMT2A | |
| SCHEMBL9077656 | 0.75 | FBP1 (0.50) | ALDH1A1GPR35KMT2AMEN1TDP1 | |
| SCHEMBL10659350 | 0.74 | HTT (0.56) | HTTPOLBALDH1A1GPR35KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2486115-A1 | ELECTRORHEOLOGICAL FLUID COMPRISING ORGANIC DOPANTS, AND USE THEREOF | Fraunhofer Gesellschaft zur Förderung der angewandten Wissenschaft E.V. (DE) | 2012-08-15 | — | — | EP | claimed |
| WO-2011042117-A1 | ELECTRORHEOLOGICAL FLUID COMPRISING ORGANIC DOPANTS, AND USE THEREOF | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) | 2011-04-14 | — | — | WO | claimed |