SCHEMBL16684236

SCHEMBL16684236

Cc1ccc(/N=N/c2c(N)ccc3ccccc23)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 7/20 0.56
▸ MEN1 O00255 7/20 0.56
▸ KMT2A Q03164 7/20 0.56
▸ NPC1 O15118 7/20 0.56
▸ RAB9A P51151 5/20 0.56
▸ SENP7 Q9BQF6 2/20 0.51
▸ SENP2 Q9HC62 2/20 0.51
▸ SENP1 Q9P0U3 2/20 0.51
▸ SUMO2 P61956 1/20 0.51
▸ SUMO1 P63165 1/20 0.51
▸ SENP3 Q9H4L4 1/20 0.51
▸ MAPT P10636 9/20 0.50
▸ TDP1 Q9NUW8 6/20 0.50
▸ LMNA P02545 2/20 0.50
▸ GAA P10253 2/20 0.50
▸ ALPL P05186 1/20 0.50
▸ HSP90AA1 P07900 1/20 0.50
▸ ALPI P09923 1/20 0.50
▸ ALPG P10696 1/20 0.50
▸ CASP3 P42574 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10999478 0.88 THRB (0.62) L3MBTL1MEN1KMT2ANPC1RAB9A
SCHEMBL10999474 0.88 THRB (0.62) L3MBTL1MEN1KMT2ANPC1RAB9A
SCHEMBL295205 0.86 THRB (0.64) L3MBTL1MEN1KMT2ANPC1RAB9A
SCHEMBL295204 0.86 THRB (0.64) L3MBTL1MEN1KMT2ANPC1RAB9A
SCHEMBL29387910 0.86 THRB (0.64) L3MBTL1MEN1KMT2ANPC1RAB9A
SCHEMBL28060056 0.86 SENP2 (0.53) L3MBTL1MEN1KMT2ANPC1RAB9A
SCHEMBL12706058 0.84 SENP7 (0.51) L3MBTL1MEN1KMT2ANPC1RAB9A
SCHEMBL11695313 0.82 SENP2 (0.59) L3MBTL1MEN1KMT2ANPC1RAB9A
SCHEMBL11143645 0.81 MAPT (0.77) L3MBTL1MEN1KMT2ANPC1RAB9A
SCHEMBL4751325 0.81 MAPT (0.77) L3MBTL1MEN1KMT2ANPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150119356-A1 Ophthalmic Viscoelastic Device CARL ZEISS MEDITEC AG (DE) 2015-04-30 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150119356-A1 Ophthalmic Viscoelastic Device UACA, ICAM1, VIM L3MBTL1 4780/4885MEN1 3876/4885KMT2A 3415/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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