Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.44 |
| ▸ | THRA | P10827 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1668341 | 0.94 | FFAR4 (0.45) | FFAR4FFAR1THRATHRBRAB9A | |
| SCHEMBL24894486 | 0.82 | CYP4F2 (0.51) | FFAR1SMN1; SMN2 | |
| SCHEMBL30074373 | 0.82 | CYP4F2 (0.51) | FFAR1SMN1; SMN2 | |
| SCHEMBL13225831 | 0.82 | FFAR1 (0.56) | FFAR4FFAR1 | |
| SCHEMBL3590948 | 0.80 | TDP1 (0.49) | FFAR1APP | |
| SCHEMBL1559211 | 0.78 | CTSB (0.42) | FFAR4FFAR1THRATHRB | |
| SCHEMBL1670717 | 0.78 | YAP1 (0.45) | THRBSMN1; SMN2 | |
| SCHEMBL12800828 | 0.77 | OPRD1 (0.39) | FFAR4FFAR1APPCYP2C9PTGER1 | |
| SCHEMBL16050838 | 0.77 | FFAR4 (0.57) | FFAR4FFAR1THRATHRBRAB9A | |
| SCHEMBL27821150 | 0.77 | FFAR4 (0.51) | FFAR4FFAR1THRATHRBRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011048409-A1 | CYCLIC AMINE DERIVATIVES HAVING BETA2 ADRENERGIC RECEPTOR AGONIST AND MUSCARINIC RECEPTOR ANTAGONIST ACTIVITY | ASTRAZENECA AB (SE) | 2011-04-28 | — | — | WO | disclosed |