Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | THRA | P10827 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.39 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.39 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.39 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1668504 | 0.94 | FFAR4 (0.46) | FFAR4FFAR1MTNR1AMTNR1BAPP | |
| SCHEMBL1668747 | 0.80 | YAP1 (0.40) | FFAR4MTNR1AMTNR1BAPPRAB9A | |
| SCHEMBL1669343 | 0.77 | OPRD1 (0.40) | FFAR4FFAR1MTNR1AMTNR1BAPP | |
| SCHEMBL25310129 | 0.77 | L3MBTL1 (0.55) | L3MBTL1 | |
| SCHEMBL24757005 | 0.77 | L3MBTL1 (0.55) | L3MBTL1 | |
| SCHEMBL40228 | 0.77 | HDAC6 (0.44) | — | |
| SCHEMBL12800403 | 0.77 | OPRD1 (0.46) | FFAR4 | |
| SCHEMBL30074373 | 0.76 | CYP4F2 (0.51) | FFAR1SMN1; SMN2 | |
| SCHEMBL24894486 | 0.76 | CYP4F2 (0.51) | FFAR1SMN1; SMN2 | |
| SCHEMBL26115731 | 0.76 | L3MBTL1 (0.60) | L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011048409-A1 | CYCLIC AMINE DERIVATIVES HAVING BETA2 ADRENERGIC RECEPTOR AGONIST AND MUSCARINIC RECEPTOR ANTAGONIST ACTIVITY | ASTRAZENECA AB (SE) | 2011-04-28 | — | — | WO | disclosed |