Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | HTR5A | P47898 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16684950 | 0.89 | DRD2 (0.41) | DRD2DRD4DRD3HTR5AALOX5 | |
| SCHEMBL16684946 | 0.82 | ALOX5 (0.37) | DRD2ALOX5 | |
| SCHEMBL16684902 | 0.79 | ALOX5 (0.43) | DRD2DRD4DRD3HTR5AALOX5 | |
| SCHEMBL16685002 | 0.74 | ALOX5 (0.39) | DRD2ALOX5 | |
| SCHEMBL15321059 | 0.71 | — | — | |
| SCHEMBL16685119 | 0.71 | DRD2 (0.46) | DRD2DRD4DRD3HTR5AALOX5 | |
| Hydrochloric Acid SCHEMBL15321894 | 0.70 | — | — | |
| SCHEMBL28369370 | 0.70 | KMT2A (0.53) | — | |
| SCHEMBL8261364 | 0.69 | HTR5A (0.41) | HTR5A | |
| SCHEMBL16684943 | 0.69 | HPGD (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015066344-A1 | 5-HT2C RECEPTOR AGONISTS AND COMPOSITIONS AND METHODS OF USE | ARENA PHARMACEUTICALS, INC. (US) | 2015-05-07 | — | — | WO | disclosed |