Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16685007 | 0.86 | GAA (0.37) | POLBADRA1DADRA1AADRA1BGAA | |
| SCHEMBL16684794 | 0.80 | KDM4E (0.33) | HPGDKDM4E | |
| SCHEMBL16684908 | 0.72 | POLB (0.35) | ALDH1A1POLBTSHRHTTKDM4E | |
| SCHEMBL16685117 | 0.69 | HTR2A (0.38) | — | |
| SCHEMBL16685133 | 0.69 | DRD2 (0.42) | — | |
| SCHEMBL16684950 | 0.68 | DRD2 (0.41) | POLBTSHRKDM4E | |
| SCHEMBL16691526 | 0.66 | HTR2C (0.59) | ALDH1A1KDM4E | |
| SCHEMBL16691502 | 0.66 | HTR2C (0.59) | ALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL16687125 | 0.66 | HTR2C (0.58) | ALDH1A1KDM4E | |
| SCHEMBL16684897 | 0.66 | CCKBR (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015066344-A1 | 5-HT2C RECEPTOR AGONISTS AND COMPOSITIONS AND METHODS OF USE | ARENA PHARMACEUTICALS, INC. (US) | 2015-05-07 | — | — | WO | disclosed |