Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.70 |
| ▸ | MAOB | P27338 | 1/20 | 0.70 |
| ▸ | CDC25B | P30305 | 1/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.52 |
| ▸ | MAPT | P10636 | 6/20 | 0.52 |
| ▸ | BLM | P54132 | 5/20 | 0.52 |
| ▸ | TP53 | P04637 | 3/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.52 |
| ▸ | CASP1 | P29466 | 3/20 | 0.52 |
| ▸ | CASP7 | P55210 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.50 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.43 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.41 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.41 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31112247 | 0.94 | MAOA (0.77) | MAOAMAOBCDC25BSMN1; SMN2MAPT | |
| SCHEMBL20618218 | 0.94 | MAOA (0.77) | MAOAMAOBCDC25BSMN1; SMN2MAPT | |
| SCHEMBL19013209 | 0.91 | MAOA (0.87) | MAOAMAOBCDC25BSMN1; SMN2MAPT | |
| SCHEMBL30616365 | 0.89 | MAOA (0.86) | MAOAMAOBCDC25BSMN1; SMN2MAPT | |
| SCHEMBL30956639 | 0.89 | MAOA (0.70) | MAOAMAOBCDC25BSMN1; SMN2MAPT | |
| SCHEMBL8417659 | 0.89 | MAOA (0.86) | MAOAMAOBCDC25BSMN1; SMN2MAPT | |
| SCHEMBL6926901 | 0.85 | MAOA (0.95) | MAOAMAOBCDC25BSMN1; SMN2MAPT | |
| SCHEMBL9269089 | 0.83 | MAOA (0.77) | MAOAMAOBCDC25BSMN1; SMN2MAPT | |
| SCHEMBL29350676 | 0.82 | MAOA (1.00) | MAOAMAOBCDC25BSMN1; SMN2MAPT | |
| SCHEMBL421291 | 0.82 | MAOA (1.00) | MAOAMAOBCDC25BSMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118255765-A | Spiro nitrogen-containing compound and application thereof | 安徽晶凯电子材料有限公司 | 2024-06-28 | — | — | CN | disclosed |
| US-10002214-B2 | Host materials and ligands for dopants in organic light emitting diodes | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2018-06-19 | — | — | US | disclosed |
| US-20160232265-A1 | HOST MATERIALS AND LIGANDS FOR DOPANTS IN ORGANIC LIGHT EMITTING DIODES | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2016-08-11 | — | — | US | disclosed |
| WO-2015066244-A1 | HOST MATERIALS AND LIGANDS FOR DOPANTS IN ORGANIC LIGHT EMITTING DIODES | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2015-05-07 | — | — | WO | disclosed |