Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.95 |
| ▸ | MAOB | P27338 | 1/20 | 0.95 |
| ▸ | CDC25B | P30305 | 2/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | BLM | P54132 | 3/20 | 0.52 |
| ▸ | PTPRC | P08575 | 3/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | S100A4 | P26447 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | CES2 | O00748 | 1/20 | 0.52 |
| ▸ | APAF1 | O14727 | 1/20 | 0.52 |
| ▸ | TERT | O14746 | 1/20 | 0.52 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.52 |
| ▸ | TDP2 | O95551 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29350676 | 0.98 | MAOA (1.00) | MAOAMAOBCDC25BMEN1KMT2A | |
| SCHEMBL421291 | 0.98 | MAOA (1.00) | MAOAMAOBCDC25BMEN1KMT2A | |
| SCHEMBL19013209 | 0.95 | MAOA (0.87) | MAOAMAOBCDC25BMEN1KMT2A | |
| SCHEMBL3066734 | 0.95 | MAOA (0.87) | MAOAMAOBCDC25BMEN1KMT2A | |
| SCHEMBL31112247 | 0.91 | MAOA (0.77) | MAOAMAOBCDC25BMEN1KMT2A | |
| SCHEMBL20618218 | 0.91 | MAOA (0.77) | MAOAMAOBCDC25BMEN1KMT2A | |
| SCHEMBL8417659 | 0.91 | MAOA (0.86) | MAOAMAOBCDC25BMEN1KMT2A | |
| SCHEMBL30616365 | 0.91 | MAOA (0.86) | MAOAMAOBCDC25BMEN1KMT2A | |
| SCHEMBL16685145 | 0.85 | MAOA (0.70) | MAOAMAOBCDC25BMEN1KMT2A | |
| SCHEMBL9269089 | 0.85 | MAOA (0.77) | MAOAMAOBCDC25BMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-53052428-A | — | — | None | — | — | JP | disclosed |
| CN-111808023-B | Method for preparing 3-aryl isoquinoline derivative | 四川大学 | 2022-10-21 | — | — | CN | disclosed |
| CN-106831581-B | Azaspiro-bifluorene derivative and preparation method thereof | 上海大学 | 2021-07-09 | — | — | CN | disclosed |
| CN-110132915-B | Aggregation-induced emission probe and method for dual detection of heavy metal ion pollutants | 华南理工大学 | 2020-09-22 | — | — | CN | disclosed |
| US-20190312210-A1 | ORGANIC ELECTROLUMINESCENCE DEVICE AND POLYCYCLIC COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE | SAMSUNG DISPLAY CO., LTD. (KR) | 2019-10-10 | — | — | US | disclosed |
| US-6515011-B2 | Anticoagulants | MERCK & CO., INC. | 2003-02-04 | — | — | US | disclosed |
| US-20020119992-A1 | Thrombin inhibitors | MERCK & CO., INC. | 2002-08-29 | — | — | US | disclosed |
| WO-2002050056-A1 | BENZYLAMINE DERIVATIVES AND THEIR USE AS THROMBIN INHIBITORS | MERCK & CO., INC. (US) | 2002-06-27 | — | — | WO | disclosed |
| US-5434264-A | α,α-disubstituted aromatics and heteroaromatics as cognition enhancers | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1995-07-18 | — | — | US | disclosed |
| WO-1994009002-A1 | 2-(AZA-9-FLUORENONYL)CARBAPENEM ANTIBACTERIAL AGENTS | MERCK & CO., INC. (US) | 1994-04-28 | — | — | WO | disclosed |
| US-4740602-A | Indole derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1988-04-26 | — | — | US | disclosed |
| US-4717725-A | SPIROCYCLIC AROMATIC IMIDES | ALCON LABORATORIES, INC. (US) | 1988-01-05 | — | — | US | disclosed |
| EP-0206225-A2 | Indole derivatives | MERCK PATENT GmbH (DE) | 1986-12-30 | — | — | EP | disclosed |
| US-4537892-A | ANTIDIABETIC AGENTS | ALCON LABORATORIES, INC. (US) | 1985-08-27 | — | — | US | disclosed |
| EP-0137333-A2 | Spiro-tricyclicaromatic succinimide derivatives as inhibitors of aldose reductase | ALCON LABORATORIES, INC. (US) | 1985-04-17 | — | — | EP | disclosed |
| US-4446217-A | Electrophotographic photosensitive member having a hydrazone containing layer | CANON KABUSHIKI KAISHA (JP) | 1984-05-01 | — | — | US | disclosed |
| US-4399208-A | PHENYL HYDRAZONES | CANON KABUSHIKI KAISHA (JP) | 1983-08-16 | — | — | US | disclosed |
| JP-S5352428-A | PHOTOCONDUCTIVE LIGHT SENSITIVE ELEMENT | RICOH CO LTD | 1978-05-12 | — | — | JP | disclosed |
| US-3984378-A | PHOTOCONDUCTIVE FILMS | KABUSHIKI KAISHA RICOH (JA) | 1976-10-05 | — | — | US | disclosed |
| US-3974167-A | (7-Nitro-2-aza-9-fluorenylidene) malononitrile | RICOH CO., LTD. (JA) | 1976-08-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190312210-A1 | ORGANIC ELECTROLUMINESCENCE DEVICE AND POLYCYCLIC COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE | SLCO4C1, SLCO2A1, SLCO1A2 | MAOA 957/4885MAOB 1244/4885CDC25B 2775/4885 |
| US-20020119992-A1 | Thrombin inhibitors | SERPINC1, F2, TFPI | MAOA 3009/4885MAOB 2230/4885CDC25B 2258/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.