Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ACP3 | P15309 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 2/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18042368 | 1.00 | ESR1 (0.45) | ESR1ADRA2AADRA2BADRA2CALDH1A1 | |
| SCHEMBL18411491 | 0.82 | ALDH1A1 (0.33) | ESR1ALDH1A1L3MBTL1TSHR | |
| SCHEMBL6258207 | 0.79 | MC4R (0.40) | ALDH1A1L3MBTL1CA1CA2 | |
| SCHEMBL7663623 | 0.79 | LPAR1 (0.40) | ALDH1A1L3MBTL1LMNA | |
| SCHEMBL15273965 | 0.79 | L3MBTL1 (0.37) | ALDH1A1L3MBTL1ACHECA1CA2 | |
| SCHEMBL7261205 | 0.79 | CA1 (0.51) | ALDH1A1L3MBTL1ACHECA1CA2 | |
| SCHEMBL15562148 | 0.77 | ALDH1A1 (0.44) | ADRA2AADRA2BADRA2CALDH1A1SLC6A4 | |
| SCHEMBL22243589 | 0.75 | PSEN1 (0.35) | ALDH1A1POLBTSHR | |
| SCHEMBL16629394 | 0.75 | PSEN1 (0.38) | ALDH1A1 | |
| SCHEMBL18002519 | 0.75 | ACP3 (0.40) | L3MBTL1ACP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9987381-B2 | Radioligands for imaging the LPA-1 receptor | BRISTOL-MYERS SQUIBB COMPANY (US) | 2018-06-05 | — | — | US | disclosed |
| US-20160256577-A1 | RADIOLIGANDS FOR IMAGING THE LPA-1 RECEPTOR | BRISTOL MYERS SQUIBB CO (US) | 2016-09-08 | — | — | US | disclosed |
| EP-3062827-A1 | RADIOLIGANDS FOR IMAGING THE LPA-1 RECEPTOR | Bristol-Myers Squibb Company (US) | 2016-09-07 | — | — | EP | disclosed |
| WO-2015066456-A1 | RADIOLIGANDS FOR IMAGING THE LPA-1 RECEPTOR | BRISTOL-MYERS SQUIBB COMPANY (US) | 2015-05-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160256577-A1 | RADIOLIGANDS FOR IMAGING THE LPA-1 RECEPTOR | LPAR1, LPAR3, LPAR2 | ESR1 3531/4885ADRA2A 201/4885ADRA2B 177/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.