Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
| ▸ | SCN1A | P35498 | 3/20 | 0.39 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.39 |
| ▸ | SCN8A | Q9UQD0 | 3/20 | 0.39 |
| ▸ | IGLV6-57 | P01721 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3887578 | 0.84 | CYP3A4 (0.42) | MC4RCYP3A4CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL28873412 | 0.80 | MC4R (0.40) | MC4RCYP3A4L3MBTL1ALDH1A1MEN1 | |
| SCHEMBL1604902 | 0.79 | ALDH1A1 (0.38) | SCN1ASCN5ASCN8AALDH1A1CES2 | |
| SCHEMBL18042368 | 0.79 | ESR1 (0.45) | L3MBTL1ALDH1A1CA1CA2 | |
| SCHEMBL16685290 | 0.79 | ESR1 (0.45) | L3MBTL1ALDH1A1CA1CA2 | |
| SCHEMBL779565 | 0.78 | CA12 (0.43) | MC4RCYP3A4CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL7261205 | 0.78 | CA1 (0.51) | L3MBTL1ALDH1A1MEN1KMT2ACA12 | |
| SCHEMBL15273965 | 0.78 | L3MBTL1 (0.37) | L3MBTL1ALDH1A1CA12CA1CA2 | |
| SCHEMBL7663623 | 0.78 | LPAR1 (0.40) | CYP3A4SCN1ASCN5ASCN8AL3MBTL1 | |
| SCHEMBL20303483 | 0.77 | PSEN1 (0.44) | CYP3A4SCN1ASCN5ASCN8A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050215435-A1 | Phenylalanine derivatives as herbicides | BASF AKTIENGESELLSCHAFT (DE) | 2005-09-29 | — | — | US | disclosed |
| EP-1474381-B1 | PHENYLALANINE DERIVATIVES AS HERBICIDES | BASF AG (DE) | 2005-09-28 | — | — | EP | disclosed |
| EP-1474381-A1 | PHENYLALANINE DERIVATIVES AS HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 2004-11-10 | — | — | EP | disclosed |
| WO-2003066576-A1 | PHENYLALANINE DERIVATIVES AS HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 2003-08-14 | — | — | WO | disclosed |
| EP-0144729-B1 | 11-Substituted 5H,11H-pyrrolo[2,1-c][1,4]benzoxazepines, a process for their preparation and their use in medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1989-11-08 | — | — | EP | disclosed |
| US-4681879-A | 11-substituted 5H,11H-pyrrolo[2,1-c][1,4]benzoxazepines as antipsychotic and analgesic agents | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1987-07-21 | — | — | US | disclosed |
| US-4608374-A | 11-substituted 5H,11H-pyrrolo[2,1-c][1,4]benzoxazepines as antipsychotic and analgesic agents | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1986-08-26 | — | — | US | disclosed |
| EP-0144729-A1 | 11-Substituted 5H,11H-pyrrolo[2,1-c][1,4]benzoxazepines, a process for their preparation and their use in medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1985-06-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050215435-A1 | Phenylalanine derivatives as herbicides | PAH, DDT, HPD | MC4R 526/4885CYP3A4 315/4885CHRNB2 3655/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.