Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9401933 | 0.85 | CYP2C9 (0.43) | ALDH1A1CYP1A2CYP2C9CYP2C19SLC6A4 | |
| SCHEMBL9740708 | 0.82 | ALDH1A1 (0.41) | ALDH1A1CYP1A2CYP2C9CYP2C19SLC6A4 | |
| SCHEMBL11672371 | 0.81 | ALDH1A1 (0.54) | ALDH1A1CYP1A2CYP2C9CYP2C19SLC6A4 | |
| Ammonia Solution, Strong SCHEMBL28352063 | 0.80 | CYP2C9 (0.39) | ALDH1A1CYP1A2CYP2C9CYP2C19SLC6A4 | |
| SCHEMBL6492647 | 0.80 | ALDH1A1 (0.52) | ALDH1A1CYP1A2CYP2C9CYP2C19KEAP1 | |
| SCHEMBL17184098 | 0.79 | ALDH1A1 (0.43) | ALDH1A1KEAP1 | |
| SCHEMBL6248166 | 0.77 | ALDH1A1 (0.54) | ALDH1A1CYP1A2CYP2C9CYP2C19SLC6A4 | |
| SCHEMBL6656867 | 0.77 | ALDH1A1 (0.42) | ALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL16685290 | 0.77 | ESR1 (0.45) | ALDH1A1SLC6A4ADRA2AADRA2BADRA2C | |
| SCHEMBL18042368 | 0.77 | ESR1 (0.45) | ALDH1A1SLC6A4ADRA2AADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9856182-B2 | Radiofluorination method | TECHNICAL UNIVERSITY OF DENMARK (DK) | 2018-01-02 | — | — | US | disclosed |
| EP-2880005-B1 | RADIOFLUORINATION METHOD | UNIV DENMARK TECH DTU (DK) | 2016-05-25 | — | — | EP | disclosed |
| US-20150299066-A1 | RADIOFLUORINATION METHOD | TECHNICAL UNIVERSITY OF DENMARK (DK) | 2015-10-22 | — | — | US | disclosed |
| EP-2880005-A1 | RADIOFLUORINATION METHOD | Technical University of Denmark (DK) | 2015-06-10 | — | — | EP | disclosed |
| WO-2014020035-A1 | RADIOFLUORINATION METHOD | TECHNICAL UNIVERSITY OF DENMARK (DK) | 2014-02-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150299066-A1 | RADIOFLUORINATION METHOD | PFAS, PHOSPHO1, ARFGEF1 | ALDH1A1 4335/4885CYP1A2 3014/4885CYP2C9 2708/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.